Listar Grupo de investigación na regulación da expresión xénica en levaduras e as súas aplicacións (EXPRELA) por data de publicación

Mostrando ítems 21-29 de 29

    • Reactivity of a Recombinant Esterase from Thermus thermophilus HB27 in Aqueous and Organic Media 

      González González, Roberto; Fuciños, Pablo; Beneventi, Elisa; López-López, Olalla; Pampín, Begoña; Rodríguez, Ramón; González-Siso, María-Isabel; Cruces, Jacobo; Rúa Rodríguez, María Luisa (MDPI, 2022-04-27)
      [Abstract] The thermoalkalophilic membrane-associated esterase E34Tt from Thermus thermophilus HB27 was cloned and expressed in Kluyveromyces lactis (KLEST-3S esterase). The recombinant enzyme was tested as a biocatalyst ...

    • Bioprospecting for Thermozymes and Characterization of a Novel Lipolytic Thermozyme Belonging to the SGNH/GDSL Family of Hydrolases 

      Escuder-Rodríguez, Juan-José; De Castro de Antonio, María Eugenia; Saavedra-Bouza, Almudena; González-Siso, María-Isabel; Becerra, Manuel (MDPI, 2022-05-20)
      [Abstract] Functional screenings were conducted on two metagenomic libraries from hot springs in order to find novel thermozymes with potential biotechnological applications. These included enzymes acting on plant cell ...

    • Insights on Microbial Communities Inhabiting Non-Volcanic Hot Springs 

      Escuder-Rodríguez, Juan-José; De Castro de Antonio, María Eugenia; Saavedra-Bouza, Almudena; Becerra, Manuel; González-Siso, María-Isabel (MDPI, 2022-10-13)
      [Abstract] The northwest of Spain has an abundance of non-volcanic hot springs that, until recently, had only been used for thermalism activities. One of such hot springs, Muiño da Veiga, has now been explored using ...

    • Role of the E3 Ubiquitin-Ligase Hakai in Intestinal Inflammation and Cancer Bowel Disease 

      Roca-Lema, Daniel; Quiroga, Macarena; Khare, Vineeta; Díaz-Díaz, Andrea; Barreiro-Alonso, Aida; Rodríguez-Alonso, Andrea; Concha, Ángel; Romay, Gabriela; Cerdán, María Esperanza; Gasche, Christoph; Figueroa, Angélica (Springer Nature, 2022-10-20)
      [Abstract] The E3 ubiquitin-ligases are important for cellular protein homeostasis and their deregulation is implicated in cancer. The E3 ubiquitin-ligase Hakai is involved in tumour progression and metastasis, through the ...

    • Xylanases From Thermophilic Archaea: A Hidden Treasure 

      Saavedra-Bouza, Almudena; Escuder-Rodríguez, Juan-José; De Castro de Antonio, María Eugenia; Becerra, Manuel; González-Siso, María-Isabel (Elsevier, 2022-12-12)
      [Abstract] Archaea are a domain of prokaryotic organisms that often inhabit extremophilic environments. Their enzymes are therefore of enormous biotechnological interest, due to their stability and activity in harsh ...

    • Study of ferroptosis transmission by small extracellular vesicles in epithelial ovarian cancer cells 

      Alarcón-Veleiro, Carmen; Mato-Basalo, Rocío; Lucio-Gallego, Sergio; Vidal-Pampín, Andrea; Quindós-Varela, María; Al-Qatarneh, Thamer; Berrecoso, Germán; Vizoso-Vázquez, Ángel; Arufe, M.C.; Fafián Labora, Juan Antonio (MDPI, 2023-01-12)
      [Abstract] Epithelial ovarian cancer (EOC) is the most lethal gynecological cancer. The current treatment for EOC involves surgical debulking of the tumors followed by a combination of chemotherapy. While most patients ...

    • Novel Microbial Enzymes with Industrial Applications [Editorial] 

      González-Siso, María-Isabel; Becerra, Manuel (MDPI, 2023-04-10)

    • Thanksgiving to Yeast, the HMGB Proteins History from Yeast to Cancer [Review] 

      Lamas, Mónica; Vizoso-Vázquez, Ángel; Barreiro-Alonso, Aida; Cámara-Quílez, M.; Cerdán, María Esperanza (MDPI, 2023-04-11)
      [Abstract] Yeasts have been a part of human life since ancient times in the fermentation of many natural products used for food. In addition, in the 20th century, they became powerful tools to elucidate the functions of ...

    • The Effect of HMGB1 and HMGB2 on Transcriptional Regulation Differs in Neuroendocrine and Adenocarcinoma Models of Prostate Cancer 

      Salamini-Montemurri, Martín; Vizoso-Vázquez, Ángel; Barreiro-Alonso, Aida; Lorenzo-Catoira, Lidia; Rodríguez-Belmonte, Esther; Cerdán, María Esperanza; Lamas, Mónica (MDPI, 2024-03-07)
      [Abstract] Human high-mobility group-B (HMGB) proteins regulate gene expression in prostate cancer (PCa), a leading cause of oncological death in men. Their role in aggressive PCa cancers, which do not respond to hormonal ...