Diagnóstico molecular e condutual aplicado á saúde (DICOMOSA): Envíos recentes

Mostrando ítems 26-30 de 41

    • Suitability of the In Vitro Cytokinesis-Block Micronucleus Test for Genotoxicity Assessment of TiO2 Nanoparticles on SH-SY5Y Cells 

      Fernández-Bertólez, Natalia; Brandão, Fátima; Costa, C.; Pásaro, Eduardo; Teixeira, João; Laffon, Blanca; Valdiglesias, Vanessa (2021)
      [Abstract] Standard toxicity tests might not be fully adequate for evaluating nanomaterials since their unique features are also responsible for unexpected interactions. The in vitro cytokinesis-block micronucleus (CBMN) ...

    • Epigenetics Is Implicated in the Basis of Gender Incongruence: An Epigenome-Wide Association Analysis 

      Ramirez, Karla; Fernández, Rosa; Collet, Sarah; Meltem, Kiyat; Delgado-Zayas, Enrique; Gómez-Gil, Esther; Van Den Eynde, Tibbert; T’Sjoen, Guy; Guillamon, Antonio; Mueller, Sven C.; Pásaro, Eduardo (2021)
      [Abstract] Introduction: The main objective was to carry out a global DNA methylation analysis in a population with gender incongruence before gender-affirming hormone treatment (GAHT), in comparison to a cisgender ...

    • “Micronuclei and Disease” special issue: Aims, scope, and synthesis of outcomes 

      Fenech, Michael; Knasmueller, Siegfried; Knudsen, Lisbeth E.; Kirsch-Volders, Micheline; Deo, Permal; Franzke, Bernhard; Stopper, Helga; Andreassi, Maria-Grazia; Bolognesi, Claudia; Dhillon, Varinderpal S.; Laffon, Blanca; Wagner, Karl-Heinz; Bonassi, Stefano (2021)
      [Abastract] The purpose of the “Micronuclei and Disease” special issue (SI) is to: (i) Determine the level of evidence for association of micronuclei (MN), a biomarker of numerical and structural chromosomal aberrations, ...

    • DNA Damage in Circulating Leukocytes Measured With the Comet Assay May Predict the Risk of Death 

      Bonassi, Stefano; Ceppi, Marcello; Møller, Peter; Azqueta, Amaya; Milić, Mirta; Neri, Monica; Brunborg, Gunnar; Godschalk, Roger; Koppen, Gudrun; Langie, Sabine; Teixeira, João; Bruzzone, Marco; Da Silva, Juliana; Benedetti, Danieli; Cavallo, Delia; Ursini, Cinzia Lucia; Giovannelli, Lisa; Moretti, Silvia; Riso, Patrizia; Del Bo’, Cristian; Russo, Patrizia; Dobrzyńska, Malgorzata; Goroshinskaya, Irina A.; Surikova, Ekaterina; Staruchova, Marta; Barančoková, Magdaléna; Volkovova, Katarina; Kažimírová, Alena; Smolkova, Bozena; Laffon, Blanca; Valdiglesias, Vanessa; Pastor, Susana; Marcos, Ricard; Hernández, Alba; Gajski, Goran; Spremo-Potparević, Biljana; Živković, Lada; Boutet-Robinet, Elisa; Perdry, Hervé; Lebailly, Pierre; Pérez, Carlos L.; Başaran, Nurşen; Nemeth, Zsuzsanna; Sáfár, Anna; Dusinska, Maria; Collins, Andrew (2021)
      [Abstract] The comet assay or single cell gel electrophoresis, is the most common method used to measure strand breaks and a variety of other DNA lesions in human populations. To estimate the risk of overall mortality, ...

    • Implications of the Estrogen Receptor Coactivators SRC1 and SRC2 in the Biological Basis of Gender Incongruence 

      Del Valle Ramírez, Karla; Fernández, Rosa; Delgado-Zayas, Enrique; Gómez-Gil, Esther; Esteva, Isabel; Guillamon, Antonio; Pásaro, Eduardo (2021)
      [Abstract] Introduction Brain sexual differentiation results from the effects of sex steroids on the developing brain. The presumptive route for brain masculinization is the direct induction of gene expression via activation ...