Listar GI-FENM - Artigos por título
Mostrando ítems 44-63 de 117
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Effects of oral glutamine during abdominal radiotherapy on chronic radiation enteritis: a randomized controlled trial
(Elsevier, 2015-01)[Abstract] Objective. Glutamine has been proposed as a preventive treatment for toxicity related to cancer therapies. The aim of this study was to test the efficacy of glutamine in the prevention of radiation enteritis. Methods. ... -
Efficacy of glutamine in the prevention of acute radiation enteritis: a randomized controlled trial
(SAGE, 2013-03-07)[Abstract] Background: Acute radiation enteritis is a common adverse effect related to radiotherapy (RT). Glutamine is an immune modulator and antioxidant amino acid that can exert a protective role in patients receiving ... -
Enzalutamide: a new prostate cancer targeted therapy against the androgen receptor
(Elsevier, 2015-03)[Abstract] Enzalutamide (MDV3100), an androgen receptor-signalling inhibitor, represents the most recent compound added to the therapeutic armamentarium for the treatment of metastatic castration-resistant prostate cancer ... -
Evaluation of the efficacy and safety of lanreotide in combination with targeted therapies in patients with neuroendocrine tumours in clinical practice: a retrospective cross-sectional analysis
(BioMed Central, 2015-07-04)[Abstract] Background. Based on the mechanism of action, combining somatostatin analogues (SSAs) with mTOR inhibitors or antiangiogenic agents may provide synergistic effects for the treatment of patients with neuroendocrine ... -
Evaluation of thyroid hormone replacement dosing in morbidly obese hypothyroid patients after bariatric surgery-induced weight loss
(MDPI, 2021-08-19)[Abstract] The most frequent endocrine disease in obese patients is hypothyroidism. To date, there are no clear data regarding what happens to the dose of levothyroxine (LT4) after bariatric surgery (BS). The objective of ... -
Fasting and postprandial plasma ghrelin levels are decreased in patients with liver failure previous to liver transplantation
(Spirnger, 2009-04-11)[Abstract] Anorexia is a problem of paramount importance in patients with advanced liver failure. Ghrelin has important actions on feeding and weight homeostasis. Concentrations of ghrelin are controversial in liver ... -
FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle
(Nature, 2016-07-19)[Abstract] Irisin is processed from fibronectin type III domain-containing protein 5 (FNDC5). However, a controversy exists concerning irisin origin, regulation and function. To elucidate the relationship between serum ... -
Fructose transporter Glut5 expression in clear renal cell carcinoma
(Spandidos, 2010-12-10)[Abstract] Renal cell carcinomas (RCC) can be subclassified for general purposes into clear cell, papillary cell, chromophobe cell carcinomas and oncocytomas. Other tumours such as collecting duct, medullary, mucinous ... -
Función endocrina en la obesidad
(Elsevier, 2011-08-06)[Resumen] La obesidad se asocia con importantes anomalías en la función endocrina. La hiper insulinemia y la resistencia a la insulina son las dos alteraciones mejor conocidas, aunque sus mecanismos y su significado clínico ... -
Ghrelin and growth hormone secretagogues, physiological and pharmacological aspect
(Bentham Science, 2009)[Abstract] The first “growth hormone secretagogues” (GHSs) were discovered by Bowers et al. in 1977. In 1996 the GHSs receptor (GHS-R 1a) was cloned. The endogenous ligand for this receptor, ghrelin, was not identified ... -
Ghrelin and lipid metabolism: key partners in energy balance
(Bioscientifica para Society for Endocrinoloogy, 2011-04-01)[Abstract] Ghrelin, the endogenous ligand of the GH secretagogue receptor, has a pleiotropic role in the modulation of energy balance. Recent evidence has demonstrated that besides its orexigenic role, ghrelin regulates ... -
Ghrelin in obesity, physiological and pharmacological considerations
(Bentham, 2013-04)[Abstract] The aim of this review is to summarize the physiological and pharmacological aspects of ghrelin. Obesity can be defined as an excess of body fat and is associated with significant disturbances in metabolic and ... -
Ghrelin neutralization during fasting-refeeding cycle impairs the recuperation of body weight and alters hepatic energy metabolism
(Elsevier, 2011)[Abstract] Ghrelin, a hormone whose levels increase during food deprivation, plays a pivotal role in the regulation of food intake, energy metabolism and storage, as well as in insulin sensitivity. Here, we investigated ... -
Glucose and lipid dysmetabolism in a rat model of prediabetes induced by a high-sucrose diet
(Multidisciplinary Dixital Publishing Institute, 2017-06-21)[Abstract] Glucotoxicity and lipotoxicity are key features of type 2 diabetes mellitus, but their molecular nature during the early stages of the disease remains to be elucidated. We aimed to characterize glucose and lipid ... -
Glucose metabolism outcomes after pituitary surgery in patients with acromegaly
(Springer Nature, 2024-06-28)[Abstract] Aim. To investigate the impact of pituitary surgery on glucose metabolism and to identify predictors of remission of diabetes after pituitary surgery in patients with acromegaly. Methods. A national multicenter ... -
Glucose transporter expression and the potential role of fructose in renal cell carcinoma: a correlation with pathological parameters
(Spandidos, 2010-07-01)[Abstract] All mammalian cells contain one or more members of the facilitative glucose transporter (GLUT) gene family. Glucose transporter membrane proteins (GLUT) regulate the movement of glucose between the extracellular ... -
Gonadotrophin-releasing hormone agonist-induced pituitary adenoma apoplexy and casual finding of a parathyroid carcinoma: a case report and review of literature
(Baishideng Publishing Group, 2019-10-26)[Absatract] BACKGROUND Pituitary apoplexy represents one of the most serious, life threatening endocrine emergencies that requires immediate management. Gonadotropin-releasing hormone agonist (GnRHa) can induce pituitary ... -
Growth hormone, ghrelin and peptide YY secretion after oral glucose administration in healthy and obese women
(Thieme, 2011-06-10)[Abstract] The mechanism of the altered GH secretion in obesity is unclear. There is evidence that oral glucose (OG) administration initially decreases and subsequently stimulates GH secretion. Ghrelin is a peptide that ... -
How a bottom-up multi-stakeholder initiative helped transform the renal replacement therapy landscape in Spain
(Springer, 2017-03-06)[Abstract] Healthcare reforms aim to change certain parts of the health system to improve quality of care, access, or financial sustainability. Traditionally, healthcare reform is understood as an action undertaken by a ... -
Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3
(Public Library of Science (PLoS), 2019-11-07)[Abstract] Mkrn3, the maternally imprinted gene encoding the makorin RING-finger protein-3, has recently emerged as putative pubertal repressor, as evidenced by central precocity caused by MKRN3 mutations in humans; ...