Grupo de investigación en Terapia Celular e Medicina Rexenerativa (TCMR): Envíos recentes
Mostrando ítems 21-25 de 147
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Generation of human immortalized chondrocytes from osteoarthritic and healthy cartilage
(The British Editorial Society of Bone & Joint Surgery, 2023-01-17)[Abstract] Aims. After a few passages of in vitro culture, primary human articular chondrocytes undergo senescence and loss of their phenotype. Most of the available chondrocyte cell lines have been obtained from cartilage ... -
In vitro study of the therapeutic potential of brown crude fucoidans in osteoarthritis treatment
(MDPI, 2022-11-17)[Abstract] Osteoarthritis, one of the most common joint degenerative pathologies, still has no cure, and current treatments, such as nonsteroidal anti-inflammatory drugs, can cause serious adverse effects when taken for a ... -
Characterization and miRNA profiling of extracellular vesicles from human osteoarthritic subchondral bone multipotential stromal cells (MSCs)
(Hindawi, 2021-10-09)[Abstract] Osteoarthritis (OA) is a heterogeneous disease in which the cross-talk between the cells from different tissues within the joint is affected as the disease progresses. Extracellular vesicles (EVs) are known to ... -
Therapy free of cells vs human mesenchymal stem cells from umbilical cord stroma to treat the inflammation in OA
(Springer, 2022-10-20)[Abstract] Osteoarthritis (OA) is closely linked to the increase in the number of senescent cells in joint tissues, and the senescence-associated secretory phenotype (SASP) is implicated in cartilage degradation. In the ... -
Chondrogenic differentiation of human mesenchymal stem cells via SOX9 delivery in cationic niosomes
(MDPI, 2022-10-28)[Abstract] Gene transfer to mesenchymal stem cells constitutes a powerful approach to promote their differentiation into the appropriate cartilage phenotype. Although viral vectors represent gold standard vehicles, because ...