Grupo de investigación en Terapia Celular e Medicina Rexenerativa (TCMR): Envíos recentes
Mostrando ítems 116-120 de 147
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iTRAQ-Based Analysis of Progerin Expression Reveals Mitochondrial Dysfunction, Reactive Oxygen Species Accumulation and Altered Proteostasis
(BioMed Central, 2015-06-12)[Abstract] Introduction. Nuclear accumulation of a mutant form of the nuclear protein Lamin-A, called Progerin (PG) or Lamin AΔ50, occurs in Hutchinson-Gilford Progeria Syndrome (HGPS) or Progeria, an accelerated aging ... -
Ovine mesenchymal stromal cells: morphologic, phenotypic and functional characterization for osteochondral tissue engineering
(PLoS ONE, 2017-01-31)[Abstract] Introduction. Knowledge of ovine mesenchymal stromal cells (oMSCs) is currently expanding. Tissue engineering combining scaffolding with oMSCs provides promising therapies for the treatment of osteochondral ... -
Notch signalling in cancer stem cells
(Springer, 2009)[Abstract] A new theory about the development of solid tumours is emerging from the idea that solid tumours, like normal adult tissues, contain stem cells (called cancer stem cells) and arise from them. Genetic mutations ... -
Biology of BMP signalling and cancer
(Springer, 2009)[Abstract] In recent years, it has been proposed that tumours are not homogeneous but composed of several cellular types like normal tissues. A cellular subtype, which is though to be the origin of tumours as well as their ... -
Wnt signalling and cancer stem cells
(Springer, 2009-07-15)[Abstract] Intracellular signalling mediated by secreted Wnt proteins is essential for the establishment of cell fates and proper tissue patterning during embryo development and for the regulation of tissue homeostasis and ...