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Hedgehog signalling as a target in cancer stem cells
(Spirnger, 2009)
[Abstract] Hedgehog (Hh) is one of the most important signalling pathways. Together with the Wnt, TGF-β/BMP and Notch pathways, it is involved in both embryonic development and adult tissue homeostasis. This is because Hh ...
Biology of BMP signalling and cancer
(Springer, 2009)
[Abstract] In recent years, it has been proposed that tumours are not homogeneous but composed of several cellular types like normal tissues. A cellular subtype, which is though to be the origin of tumours as well as their ...