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Current trends in viral gene therapy for human orthopaedic regenerative medicine
(Springer, 2019-02-21)
[Abstract] Background: Viral vector-based therapeutic gene therapy is a potent strategy to enhance the intrinsic reparative abilities of human orthopaedic tissues. However, clinical application of viral gene transfer remains ...
PEO-PPO-PEO tri-block copolymers for gene delivery applications in human regenerative medicine: an overview
(MDPI, 2018-03-08)
[Abstract] Lineal (poloxamers or Pluronic®) or X-shaped (poloxamines or Tetronic®) amphiphilic tri-block copolymers of poly(ethylene oxide) and poly(propylene oxide) (PEO-PPO-PEO) have been broadly explored for controlled ...