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Parameter estimation in large-scale systems biology models: a parallel and self-adaptive cooperative strategy
(BioMed Central Ltd., 2017)
[Abstract]
Background
The development of large-scale kinetic models is one of the current key issues in computational systems biology and bioinformatics. Here we consider the problem of parameter estimation in nonlinear ...
A parallel metaheuristic for large mixed-integer dynamic optimization problems, with applications in computational biology
(Public Library of Science, 2017)
[Abstract]
Background:
We consider a general class of global optimization problems dealing with nonlinear dynamic models. Although this class is relevant to many areas of science and engineering, here we are interested ...
A cloud-based enhanced differential evolution algorithm for parameter estimation problems in computational systems biology
(Springer New York LLC, 2017)
[Abstract] Metaheuristics are gaining increasing recognition in many research areas, computational systems biology among them. Recent advances in metaheuristics can be helpful in locating the vicinity of the global solution ...