Fluorescence study of tetracaine–cyclodextrin inclusion complexes
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TitleFluorescence study of tetracaine–cyclodextrin inclusion complexes
Iglesias-García I, Brandariz I, Iglesias E. Fluorescence study of tetracaine-cyclodextrin inclusion complexes. Supramolecular Chemistry. 2010;22(4):228-36.
The steady-state fluorescence emission from the local anaesthetic tetracaine (TCA) in water-solvent mixtures and in the presence of α-, β- and γ-cyclodextrin (CD) was investigated at various pH values. Emission was observed from the locally and the intramolecular charge transfer excited states. The TCA-CD system was found to be characterised by 1:1 associate in every case. The association constants of each complex were determined.
This is an Accepted Manuscript of an article published by Taylor & Francis Group in Supramolecular Chemistry on Volume 22, Issue 4, April 2010, available online at: http://www.tandfonline.com/10.1080/10610270903304400