Fluorescence study of tetracaine–cyclodextrin inclusion complexes

Iglesias García, Iván.; Brandariz, Isabel; Iglesias, Emilia

Title

Author(s)

Iglesias García, Iván.

Brandariz, Isabel

Iglesias, Emilia

Date

2010-04

Citation

Iglesias-García I, Brandariz I, Iglesias E. Fluorescence study of tetracaine-cyclodextrin inclusion complexes. Supramolecular Chemistry. 2010;22(4):228-36.

Abstract

The steady-state fluorescence emission from the local anaesthetic tetracaine (TCA) in water-solvent mixtures and in the presence of α-, β- and γ-cyclodextrin (CD) was investigated at various pH values. Emission was observed from the locally and the intramolecular charge transfer excited states. The TCA-CD system was found to be characterised by 1:1 associate in every case. The association constants of each complex were determined.

Keywords

Stability constants
Tetracaine
Cyclodextrins
Fluorescence

Editor version

http://dx.doi.org/10.1080/10610270903304400

Rights

This is an Accepted Manuscript of an article published by Taylor & Francis Group in Supramolecular Chemistry on Volume 22, Issue 4, April 2010, available online at: http://www.tandfonline.com/10.1080/10610270903304400