Recent Submissions

  • Relative Configuration of Micrograms of Natural Compounds Using Proton Residual Chemical Shift Anisotropy 

    Nath, Nilamoni; Fuentes-Monteverde, Juan Carlos; Pech-Puch, Dawrin; Rodríguez, Jaime; Jiménez, Carlos; Noll, Markus; Kreiter, Alexander; Reggelin, Michael; Navarro-Vázquez, Armando; Griesinger, Christian (Nature, 2020-09-01)
    [Abstract] 3D molecular structure determination is a challenge for organic compounds or natural products available in minute amounts. Proton/proton and proton/carbon correlations yield the constitution. J couplings and ...
  • Antiviral and Antiproliferative Potential of Marine Organisms from the Yucatan Peninsula, Mexico 

    Pech-Puch, Dawrin; Berastegui-Cabrera, Judith; Pérez Povedano, Mar Anabel; Villegas-Hernández, Harold; Guillén-Hernández, Sergio; Cautain, Bastien; Reyes, Fernando; Pachón, Jerónimo; Gómez, Patricia; Rodríguez, Jaime; Jiménez, Carlos; Sánchez-Céspedes, Javier (Frontiers, 2020-08-20)
    [Abstract] Viral infections are one of the main human health problems in recent decades and the cancer remains one of the most lethal diseases worldwide. The development of new antiviral drugs for the treatment of human ...
  • Marine Organisms from the Yucatan Peninsula (Mexico) as a Potential Natural Source of Antibacterial Compounds 

    Pech-Puch, Dawrin; Pérez Povedano, Mar Anabel; Gómez, Patricia; Martínez-Guitián, Marta; Lasarte-Monterrubio, Cristina; Vázquez-Ucha, Juan Carlos; Novoa Olmedo, María Lourdes; Guillén-Hernández, Sergio; Villegas-Hernández, Harold; Bou, Germán; Rodríguez, Jaime; Beceiro, Alejandro; Jiménez, Carlos (MDPI, 2020-07-18)
    [Abstract] A total of 51 sponges (Porifera) and 13 ascidians (Chordata) were collected on the coast of the Yucatan Peninsula (Mexico) and extracted with organic solvents. The resulting extracts were screened for antibacterial ...
  • In vitro and in vivo assessment of the efficacy of bromoageliferin, an alkaloid isolated from the sponge "Agelas dilatata", against "Pseudomonas aeruginosa" 

    Pech-Puch, Dawrin; Pérez Povedano, Mar Anabel; Martínez-Guitián, Marta; Lasarte-Monterrubio, Cristina; Vázquez-Ucha, Juan Carlos; Bou, Germán; Rodríguez, Jaime; Beceiro, Alejandro; Jiménez, Carlos (MDPI, 2020-06-23)
    [Abstract] The pyrrole-imidazoles, a group of alkaloids commonly found in marine sponges belonging to the genus Agelas, display a wide range of biological activities. Herein, we report the first chemical study of the ...
  • Marine natural products from the Yucatan peninsula 

    Pech-Puch, Dawrin; Pérez Povedano, Mar Anabel; Lenis Rojas, Oscar; Rodríguez, Jaime; Jiménez, Carlos (MDPI AG, 2020-01-16)
    [Abstract]: Mexico is one of the three areas of the world with the greatest terrestrial and cultural biological diversity. The diversity of Mexican medicinal flora has been studied for a long time and several bioactive ...

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