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Evaluation of the in Vitro and in Vivo Efficacy of Ruthenium Polypyridyl Compounds Against Breast Cancer
(MDPI, 2021-08-18)
[Abstract] The clinical success of cisplatin, carboplatin, and oxaliplatin has sparked the interest of medicinal inorganic chemistry to synthesize and study compounds with non-platinum metal centers. Despite Ru(II)–polypyridyl ...
Antifungal Potential of Marine Organisms of the Yucatan Peninsula (Mexico) against Medically Important Candida spp.
(MDPI, 2023-01-06)
[Abstract] Invasive fungal infections represent a global health threat. They are associated with high mortality and morbidity rates, partly due to the ineffectiveness of the available antifungal agents. The rampant increase ...
Marine Natural Products from the Yucatan Peninsula
(MDPI AG, 2020-01-16)
[Abstract] Mexico is one of the three areas of the world with the greatest terrestrial and cultural biological diversity. The diversity of Mexican medicinal flora has been studied for a long time and several bioactive ...
Half-Sandwich Ru(p-cymene) Compounds with Diphosphanes: In Vitro and In Vivo Evaluation As Potential Anticancer Metallodrugs
(American Chemical Society (ACS), 2021-02-11)
[Abstract] Ruthenium(II) complexes are currently considered attractive alternatives to the widely used platinum-based drugs. We present herein the synthesis and characterization of half-sandwich ruthenium compounds formulated ...
RuII(p-cymene) Compounds as Effective and Selective Anticancer Candidates with No Toxicity in Vivo
(American Chemical Society (ACS), 2018-10-19)
[Abstract] Ruthenium(II) complexes are currently considered a viable alternative to the widely used platinum complexes as efficient anticancer agents. We herein present the synthesis and characterization of half-sandwich ...