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Evaluation of the in Vitro and in Vivo Efficacy of Ruthenium Polypyridyl Compounds Against Breast Cancer
(MDPI, 2021-08-18)
[Abstract] The clinical success of cisplatin, carboplatin, and oxaliplatin has sparked the interest of medicinal inorganic chemistry to synthesize and study compounds with non-platinum metal centers. Despite Ru(II)–polypyridyl ...
Biologically Active Peptides from Venoms: Applications in Antibiotic Resistance, Cancer, and Beyond [Review]
(MDPI, 2022-12-06)
[Abstract] Peptides are potential therapeutic alternatives against global diseases, such as antimicrobial-resistant infections and cancer. Venoms are a rich source of bioactive peptides that have evolved over time to act ...
Atypical Magnetic Behavior in the Incommensurate (CH3NH3)[Ni(HCOO)3] Hybrid Perovskite
(ACS, 2023-02-02)
[Abstract] A plethora of temperature-induced phase transitions have been observed in (CH3NH3)[M(HCOO)3] compounds, where M is Co(II) or Ni(II). Among them, the nickel compound exhibits a combination of magnetic and nuclear ...
Bioactivity and Metabolome Mining of Deep-Sea Sediment-Derived Microorganisms Reveal New Hybrid PKS-NRPS Macrolactone from Aspergillus versicolor PS108-62
(MDPI, 2023-01-28)
[Abstract] Despite low temperatures, poor nutrient levels and high pressure, microorganisms thrive in deep-sea environments of polar regions. The adaptability to such extreme environments renders deep-sea microorganisms ...
Student-Generated Videos to Promote Understanding of Chemical Reactions
(ACS, 2023-02-03)
[Abstract] Students were tasked with the creation of videos of ordinary reactions to promote significant learning of complex concepts underlying chemical transformations. Interactive infographics were used to deliver ...
Uncovering the Cyanobacterial Chemical Diversity: The Search for Novel Anticancer Compounds
(MDPI, 2022-09-15)
[Abstract] Cancer has a tremendous negative socio-economic impact on our society. Thus, the discovery of new and more effective anticancer drugs is of utmost importance. To address this societal challenge, the main goal ...
Extracellular Vesicles Enriched in Connexin 43 Promote a Senescent Phenotype in Bone and Synovial Cells Contributing to Osteoarthritis Progression
(Springer Nature, 2022)
[Abstract] The accumulation of senescent cells is a key characteristic of aging, leading to the progression of age-related diseases such as osteoarthritis (OA). Previous data from our laboratory has demonstrated that high ...
Coexistence of magnetic and electrical order in the new perovskite-like (C3N2H5)[Mn(HCOO)3] formate
(The Royal Society of Chemistry, 2013-09)
[Abstract] In this work we further the structural characterization of the recently discovered (C3N2H5)[Mn(HCOO)3] metal–organic framework with perovskite-like structure, and we present its magnetic and dielectric properties ...
Antifungal Potential of Marine Organisms of the Yucatan Peninsula (Mexico) against Medically Important Candida spp.
(MDPI, 2023-01-06)
[Abstract] Invasive fungal infections represent a global health threat. They are associated with high mortality and morbidity rates, partly due to the ineffectiveness of the available antifungal agents. The rampant increase ...
Affinity-Controlled Capture and Release of Engineered Monoclonal Antibodies by Macroporous Dextran Hydrogels Using Coiled-Coil Interactions [Report]
(Taylor & Francis, 2023-06-10)
[Abstract] Long-term delivery is a successful strategy used to reduce the adverse effects of monoclonal antibody (mAb)-based treatments. Macroporous hydrogels and affinity-based strategies have shown promising results in ...