Química molecular e de materiais (QUIMOLMAT): Envíos recentes
Mostrando ítems 6-10 de 104
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Furanoditerpenes from Spongia (Spongia) tubulifera Display Mitochondrial-Mediated Neuroprotective Effects by Targeting Cyclophilin D
(American Chemical Society, 2022-07-28)[Abstract] Neuroprotective properties of five previously described furanoditerpenes 1–5, isolated from Spongia (Spongia) tubulifera, were evaluated in an in vitro oxidative stress model in SH-SY5Y cells. Dose–response ... -
Structural Requirements for Ga3+ Coordination in Synthetic Analogues of the Siderophore Piscibactin Deduced by Chemical Synthesis and Density Functional Theory Calculations
(American Chemical Society, 2023-05-04)[Abstract] Stereoselective total synthesis of several analogues of piscibactin (Pcb), the siderophore produced by different pathogenic Gram-negative bacteria, was performed. The acid-sensitive α-methylthiazoline moiety was ... -
AHL-lactonase Expression in Three Marine Emerging Pathogenic Vibrio spp. Reduces Virulence and Mortality in Brine Shrimp (Artemia salina) and Manila Clam (Venerupis philippinarum)
(PLOS, 2018-04-17)[Abstract] Bacterial infectious diseases produced by Vibrio are the main cause of economic losses in aquaculture. During recent years it has been shown that the expression of virulence genes in some Vibrio species is ... -
The Outer Membrane Protein FstC of Aeromonas salmonicida subsp. salmonicida Acts as Receptor for Amonabactin Siderophores and Displays a Wide Ligand Plasticity. Structure–Activity Relationships of Synthetic Amonabactin Analogues
(American Chemical Society, 2019-09-26)[Abstract] Amonabactins are a group of four related catecholate siderophores produced by several species of the genus Aeromonas, including A. hydrophila and the fish pathogen A. salmonicida subsp. salmonicida. Although the ... -
The Fish Pathogen Vibrio ordalii Under Iron Deprivation Produces the Siderophore Piscibactin
(MDPI, 2019-09-03)[Abstract] Vibrio ordalii is the causative agent of vibriosis, mainly in salmonid fishes, and its virulence mechanisms are still not completely understood. In previous works we demonstrated that V. ordalii possess several ...