Browsing by Author "Méndez, Josefina"
Now showing items 1-20 of 38
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Aplicación de la genética molecular en síndrome X-frágil. Aspectos citogenéticos y conductales
Méndez, Josefina; Pásaro, Eduardo (Universidade da Coruña, 1993) -
Assessment of Okadaic Acid Effects on Cytotoxicity, DNA Damage and DNA Repair in Human Cells
Valdiglesias, Vanessa; Méndez, Josefina; Pásaro, Eduardo; Cemeli, Eduardo; Anderson, Diana; Laffon, Blanca (Elsevier, 2010-05-26)[Abstract] Okadaic acid (OA) is a phycotoxin produced by several types of dinoflagellates causing diarrheic shellfish poisoning (DSP) in humans. Symptoms induced by DSP toxins are mainly gastrointestinal, but the intoxication ... -
Birth-and-death evolution with strong purifying selection in the histone H1 multigene family and the origin of "orphon" H1 genes
Eirín-López, J.M.; González-Tizón, Ana M.; Martínez-Lage, Andrés; Méndez, Josefina (Oxford University Press, 2004-10)[Abstract:] Histones are small basic nuclear proteins with critical structural and functional roles in eukaryotic genomes. The H1 multigene family constitutes a very interesting histone class gathering the greatest number ... -
Characterization of different chromatin types in Mytilus galloprovincialis L. after C-banding, fluorochrome and restriction endonuclease treatments
Martínez-Lage, Andrés; González-Tizón, Ana M.; Méndez, Josefina (Nature, 1994-03-01)[Abstract] In this study, we have carried out the cytogenetical characterization of “Mytilus galloprovincialis” L. (2n = 28) using conventional staining and banding techniques such as fluorochromes and restriction endonucleases ... -
Chromosomal markers in three species of the genus Mytilus (Mollusca: Bivalvia)
Martínez-Lage, Andrés; González-Tizón, Ana M.; Méndez, Josefina (Nature, 1995-04-01)[Abstract] The analysis of C-banding, NOR and fluorochrome staining was carried out in three species of European mussel, "Mytilus edulis", "M. galloprovincialis" and "M. trossulus". The results obtained allow us to detect ... -
Chromosome differences between European mussel populations (genus “Mytilus”)
Martínez-Lage, Andrés; González-Tizón, Ana M.; Méndez, Josefina (Taylor & Francis, 1996)[Abstract]: We have analysed different populations of European mussels belonging to genus “Mytilus” in order to clarify the karyotype complements of these three species (“M. edulis”, “M. galloprovincialis” and “M. trossulus”). ... -
Common evolutionary origin and birth-and-death process in the replication-independent histone H1 isoforms from vertebrate and invertebrate genomes
Eirín-López, J.M.; Ruiz Lorenzo, María Fernanda; González-Tizón, Ana M.; Martínez-Lage, Andrés; Ausió, Juan; Sánchez Rodríguez, Lucas; Méndez, Josefina (Springer Nature, 2005-09)[Abstract]The H1 histone multigene family shows the greatest diversity of isoforms among the five histone gene families, including replication-dependent (RD) and replication-independent (RI) genes, according to their ... -
Comparative analysis of different satellite DNAs in four Mytilus species
Martínez-Lage, Andrés; Rodríguez Fariña, María Fernanda; González-Tizón, Ana M.; Prats, Eva; Cornudella, Luis; Méndez, Josefina (Canadian Science Publishing, 2002-10)[Abstract:] We report the characterization of three satellite DNAs in four species of mussel: Mytilus edulis, Mytilus galloprovincialis, Mytilus trossulus, and Mytilus californianus. The monomers of the Apa I satellite ... -
Cytogenetic characterization of “Donax trunculus” (Bivalvia: Donacidae) by means of karyotyping, fluorochrome banding and fluorescent “in situ” hybridization
Martínez-Lage, Andrés; Mariñas Pardo, Luis; González-Tizón, Ana M.; Méndez, Josefina (Oxford, 2002-11)[Abstract]: The chromosomes of “Donax trunculus” were analysed by means of Giemsa staining, chromomycin A3 (CA3), DAPI and fluorescent “in situ” hybridization (FISH) with an 18S-5.8S-28S rDNA probe. The diploid number is ... -
Cytogenetic Effects Induced by Prestige Oil on Human Populations: The Role of Polymorphisms in Genes Involved in Metabolism and DNA Repair
Pérez-Cadahía, Beatriz; Laffon, Blanca; Valdiglesias, Vanessa; Pásaro, Eduardo; Méndez, Josefina (Elsevier, 2008-04-18)[Abstract] The spill from the oil tanker Prestige (NW Spain, November 2002) was perhaps the biggest ecological disaster that happened worldwide in the last decades. As a consequence of this catastrophe a general concern ... -
Cytogenetics of the razor clam "Solen marginatus" (Mollusca: Bivalvia: Solenidae)
Fernández-Tajes, Juan; González-Tizón, Ana M.; Martínez-Lage, Andrés; Méndez, Josefina (Karger, 2003)[Abstract:] The razor clam Solen marginatus has a diploid chromosome number of 38. The karyotype consists of one metacentric/submetacentric, three submetacentric/metacentric, five submetacentric, one submetacentric/subtelocentric, ... -
Diagnóstico melecular. Objetivos y consideraciones finales
Méndez, Josefina (Universidade da Coruña, 1996) -
DNA content, karyotypes, and chromosomal location of 18S-5.8S-28S ribosomal loci in some species of bivalve molluscs from the Pacific Canadian coast
González-Tizón, Ana M.; Martínez-Lage, Andrés; Rego-Pérez, Ignacio; Ausió, Juan; Méndez, Josefina (Canadian Science Publishing, 2000-12)[Abstract]: The DNA content of 10 species of bivalve molluscs from British Columbia coast was determined by image analysis, and the karyotypes of the horse clam “Tressus capax”, the bent-nose macoma “Macoma nasuta”, and ... -
Early Genotoxic and Cytotoxic Effects of the Toxic Dinoflagellate Prorocentrum lima in the Mussel Mytilus galloprovincialis
Prego-Faraldo, María Verónica; Valdiglesias, Vanessa; Laffon, Blanca; Méndez, Josefina; Eirín-López, J.M. (Multidisciplinary Digital Publishing Institute, 2016)Okadaic acid (OA) and dinophysistoxins (DTXs) are the main toxins responsible for diarrhetic shellfish poisoning (DSP) intoxications during harmful algal blooms (HABs). Although the genotoxic and cytotoxic responses to OA ... -
Evaluation of Okadaic Acid-Induced Genotoxicity in Human Cells Using the Micronucleus Test and γH2AX Analysis
Valdiglesias, Vanessa; Laffon, Blanca; Pásaro, Eduardo; Méndez, Josefina (Taylor and Francis, 2011-06-27)[Abstract] Marine algal blooms have become a public health concern due to increasing frequency in the environment and severity of exposure consequences. Human intoxications produced by phycotoxins occur globally through ... -
Genetic Polymorphism in Cytochrome P450 1B1 in a Spanish Population [Short Communication]
Pérez-Cadahía, Beatriz; Valdiglesias, Vanessa; Pásaro, Eduardo; Méndez, Josefina; Laffon, Blanca (Wiley, 2007-06-02) -
Genetic Variability in Ruditapes Decussatus Clam Combined With Perkinsus Infection Level to Support Founder Population Selection for a Breeding Program
Cruz, Andreia; Costa, Fiz da; Fernández-Pérez, Jenyfer; Nantón, Ana; Fernández Boo, Sergio; Insua, Ana; Méndez, Josefina (PeerJ, 2020-10-28)[Abstract] Clam farmers worldwide face several challenges, including irregular seed supply and high mortalities due to pathogenic organisms such as "Perkinsus olseni". In Europe, there is a high unmet consumer demand for ... -
Genetic Variation of the Razor Clam Ensis Siliqua (Jeffreys, 1875) Along the European Coast Based on Random Amplified Polymorphic DNA Markers
Fernández-Tajes, Juan; Gaspar, Miguel; Martínez-Patiño, Dorotea; McDonough, Niall; Roberts, Dai; González-Tizón, Ana M.; Martínez-Lage, Andrés; Méndez, Josefina (Wiley, 2007-08)[Abstract] Ensis siliqua is regarded as an increasingly valuable fishery resource with potential for commercial aquaculture in many European countries. The genetic variation of this razor clam was analysed by randomly ... -
Los genomas eucariotas: aspectos generales
Méndez, Josefina; González-Tizón, Ana M. (Universidade da Coruña, 1997) -
Genome sizes and karyotypes in the razor clams "Ensis arcuatus" (Jeffreys, 1865) and "E. siliqua" (Linnaeus, 1758)
Fernández-Tajes, Juan; Martínez-Lage, Andrés; Freire, Ruth; Guerra, Alejandro; Méndez, Josefina; González-Tizón, Ana M. (CNRS - Station Biologique de Roscoff- ABiMS, 2008-03)[Abstract] The razor clams Ensis arcuatus and E. siliqua show a diploid DNA content of 3.85 ± 0.049 pg and 4.00 ± 0.050 pg, respectively. Both have a diploid chromosome number of 38 although their karyotypes show remarkable ...