Browsing by Author "Burguera, Elena F."
Now showing items 1-14 of 14
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Effect of balneotherapy in sulfurous water on an in vivo murine model of osteoarthritis
Vaamonde-García, Carlos; Vela-Anero, Á.; Hermida Gómez, Tamara; Burguera, Elena F.; Filgueira-Fernández, P.; Goyanes, Noa; Blanco García, Francisco J; Meijide-Faílde, Rosa (Springer, 2019-11-01)[Abstract] Osteoarthritis (OA) is a chronic joint disease that results in progressive cartilage destruction and subsequently joint dysfunction. Growing evidence indicates beneficial impact of balneological interventions ... -
Effect of hydrogen sulfide sources on inflammation and catabolic markers on interleukin 1β-stimulated human articular chondrocytes
Burguera, Elena F.; Vela-Anero, Á.; Magalhães, Joana; Meijide-Faílde, Rosa; Blanco García, Francisco J (Elsevier, 2014-07)[Abstract] Objective. Hydrogen sulfide (H2S), the third gasotransmitter together with NO and CO, is emerging as a regulator of inflammation. To test if it might offer therapeutic value in the treatment of osteoarthritis ... -
Hydrogen sulfide and inflammatory joint diseases
Burguera, Elena F.; Meijide-Faílde, Rosa; Blanco García, Francisco J (Bentham, 2017)[Abstract] Background: Rheumatoid arthritis (RA) and osteoarthritis (OA) are widespread rheumatic diseases characterized by persistent inflammation and joint destruction. Hydrogen sulfide (H2S) is an endogenous gas with ... -
Hydrogen sulfide biosynthesis is impaired in the osteoarthritic joint
Burguera, Elena F.; Vela-Anero, Á.; Gato Calvo, Lucía; Vaamonde-García, Carlos; Meijide-Faílde, Rosa; Blanco García, Francisco J (Springer, 2019-11-16)[Abstract] Osteoarthritis (OA) is the most common form of arthritis and it is a leading cause of disability in the elderly. Its complete etiology is not known although there are several metabolic, genetic, epigenetic, and ... -
Impact of prevalence ratios of chondroitin sulfate (CS)- 4 and -6 isomers derived from marine sources in cell proliferation and chondrogenic differentiation processes
López-Senra, Estefanía; Casal-Beiroa, Paula; López-Álvarez, Miriam; Serra, Julia; González, Pío; Valcárcel, Jesús; Vázquez, José Antonio; Burguera, Elena F.; Blanco García, Francisco J; Magalhães, Joana (MDPI, 2020-01-31)[Abstract] Osteoarthritis is the most prevalent rheumatic disease. During disease progression, differences have been described in the prevalence of chondroitin sulfate (CS) isomers. Marine derived-CS present a higher ... -
Impairment of hydrogen sulfide synthesis in chondrocytes under high glucose environment: a link between type 2 diabetes and osteoarthritis
Vaamonde-García, Carlos; Burguera, Elena F.; Blanco García, Francisco J; Meijide-Faílde, Rosa (Elsevier, 2018) -
In vivo and In vitro evaluation of the feasibility and safety profiles of intraarticular transplantation of mitochondria for future use as a therapy for osteoarthritis
Vaamonde-García, Carlos; Hermida Gómez, Tamara; Paniagua-Barro, Sara; Burguera, Elena F.; Blanco García, Francisco J; Fernández-Moreno, Mercedes (MDPI, 2025-01-21)[Abstract] Osteoarthritis (OA) is the most common rheumatologic disease and a major cause of pain and disability in older adults. No efficient treatment is currently available. Mitochondrial dysfunction in chondrocytes ... -
Intra-articular administration of hydrogen sulphide ameliorates severity of experimental osteoarthritis
Vela-Anero, Á.; Hermida Gómez, Tamara; Filgueira-Fernández, P.; Gato Calvo, Lucía; Burguera, Elena F.; Meijide-Faílde, Rosa; Blanco García, Francisco J (Elsevier, 2018-04-16) -
Intraarticular administration effect of hydrogen sulfide on an in vivo rat model of osteoarthritis
Vaamonde-García, Carlos; Burguera, Elena F.; Vela-Anero, Á.; Hermida Gómez, Tamara; Filgueira-Fernández, P.; Fernández-Rodríguez, Jennifer Adriana; Meijide-Faílde, Rosa; Blanco García, Francisco J (MDPI, 2020-10-08)[Abstract] Osteoarthritis (OA) is the most common articular chronic disease. However, its current treatment is limited and mostly symptomatic. Hydrogen sulfide (H2S) is an endogenous gas with recognized physiological ... -
Long-term effects of hydrogen sulfide on the anabolic-catabolic balance of articular cartilage in vitro
Vela-Anero, Á.; Hermida Gómez, Tamara; Gato Calvo, Lucía; Vaamonde-García, Carlos; Díaz-Prado, Silvia; Meijide-Faílde, Rosa; Blanco García, Francisco J; Burguera, Elena F. (Elsevier, 2017-08-15)[Abstract] Healthy cartilage maintenance relies on an equilibrium among the anabolic and catabolic processes in chondrocytes. With the onset of osteoarthritis (OA), increased interleukin (IL)-1β levels induce an inhibition ... -
Platelet-rich plasma in osteoarthritis treatment: review of current evidence
Gato Calvo, Lucía; Magalhães, Joana; Ruiz-Romero, Cristina; Blanco García, Francisco J; Burguera, Elena F. (Sage, 2019-02-19)[Abstract] Platelet-rich plasma (PRP) is defined as a volume of plasma with a platelet concentration higher than the average in peripheral blood. Many basic, preclinical and even clinical case studies and trials report ... -
Reduced levels of H₂S in diabetes-associated osteoarthritis are linked to hyperglycaemia, Nrf-2/HO-1 signalling downregulation and chondrocyte dysfunction
Piñeiro-Ramil, María; Burguera, Elena F.; Hermida Gómez, Tamara; Caramés, Beatriz; Oreiro, Natividad; Meijide-Faílde, Rosa; Blanco García, Francisco J; Vaamonde-García, Carlos (MDPI, 2022-03-25)[Abstract] Different findings indicate that type 2 diabetes is an independent risk factor for osteoarthritis (OA). However, the mechanisms underlying the connection between both diseases remain unclear. Changes in the ... -
Study of hydrogen sulfide biosynthesis in synovial tissue from diabetes-associated osteoarthritis and its influence on macrophage phenotype and abundance
Lendoiro-Cino, Natalia; Rodríguez-Coello, Arianna; Saborido, Anna; Burguera, Elena F.; Fernández-Rodríguez, Jennifer Adriana; Meijide-Faílde, Rosa; Blanco García, Francisco J; Vaamonde-García, Carlos (Springer, 2023-06-19)[Abstract] Type 2 diabetes (DB) is an independent risk factor for osteoarthritis (OA). However, the mechanisms underlying the connection between both diseases remain unclear. Synovial macrophages from OA patients with DB ... -
El sulfuro de hidrógeno ejerce efectos anti-catabólicos en cartílago articular artrósico in vitro
Burguera, Elena F.; Vela-Anero, Á.; Gato Calvo, Lucía; Blanco García, Francisco J; Meijide-Faílde, Rosa (Universidade de Vigo, 2018)[Resumen] El sulfuro de hidrógeno (H2S), compuesto activo de las aguas mineromedicinales sulfuradas, ha demostrado ser un protector tisular en varias patologías. Nuestros resultados previos demostraron que NaSH y GYY4137, ...
