Listar por autor "De-Toro, Javier"
Mostrando ítems 1-20 de 66
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3, 3′, 5-triiodo-L-thyronine increases in vitro chondrogenesis of mesenchymal stem cells from human umbilical cord stroma through SRC2
Fernández-Pernas, Pablo; Fafián Labora, Juan Antonio; Lesende-Rodríguez, Iván; Mateos, Jesús; Fuente, Alexandre de la; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Arufe, M.C. (Wiley, 2016-07-08)[Abstract] Our group focuses on the study of mesenchymal stem cells (MSCs) from human umbilical cord stroma or Warthońs jelly and their directed differentiation toward chondrocyte-like cells capable of regenerating damaged ... -
A Comparative Study of Doppler Ultrasound Against Temporal Artery Biopsy in the Diagnosis of Giant Cell Arteritis
González Porto, Sara Alicia; Silva-Díaz, María T.; Reguera Arias, Ana; Pombo-Otero, Jorge; González Rodríguez, Alba; Valero Gasalla, Javier; De-Toro, Javier (Elsevier, 2020-08-13)[Abstract] Background. Giant cell arteritis (GCA) is a vasculitis that affects medium- and large-sized arteries. Temporal artery biopsy is the gold standard for diagnosis. In view of the high demand for temporal biopsies, ... -
A survey of anatomical items relevant to the practice of rheumatology: pelvis, lower extremity, and gait
Hernández-Díaz, Cristina; Álvarez-Nemegyei, José; Navarro-Zarza, José Eduardo; Villaseñor-Ovies, Pablo; Kalish, Robert A.; Canoso, Juan J.; Vargas, Angélica; Chiapas-Gasca, Karla; Biundo, Joseph J.; De-Toro, Javier; McGonagle, Dennis; Carette, Simon; Saavedra, Miguel Ángel (Springer, 2017-06-01)[Abstract] This study aimed to generate a minimum list of structural and functional anatomical items about the pelvis/hip, knee, ankle/foot, gait, and lower limb innervation, which are most relevant to the practice of ... -
A survey of anatomical items relevant to the practice of rheumatology: upper extremity, head, neck, spine, and general concepts
Villaseñor-Ovies, Pablo; Navarro-Zarza, José Eduardo; Saavedra, Miguel Ángel; Hernández-Díaz, Cristina; Canoso, Juan J.; Biundo, Joseph J.; Kalish, Robert A.; De-Toro, Javier; McGonagle, Dennis; Carette, Simon; Álvarez-Nemegyei, José (Springer, 2016-08-18)[Abstract] This study aimed to identify the anatomical items of the upper extremity and spine that are potentially relevant to the practice of rheumatology. Ten rheumatologists interested in clinical anatomy who published, ... -
Action mechanisms of small extracellular vesicles in inflammaging
Mato Basalo, Rocío; Lucio-Gallego, Sergio; Alarcón-Veleiro, Carmen; Sacristán-Santos, Marta; Miranda Quintana, María del Pilar; Morente López, Miriam; De-Toro, Javier; Silva-Fernández, Lucía; González-Rodríguez, Alba; Arufe, M.C.; Fafián Labora, Juan Antonio (MDPI, 2022-04-06)[Abstract] The accumulation process of proinflammatory components in the body due to aging influences intercellular communication and is known as inflammaging. This biological mechanism relates the development of inflammation ... -
Adherence to synthetic disease-modifying antirheumatic drugs in rheumatoid arthritis: results of the OBSERVAR study
Juan Mas, Antonio; Castañeda, Santos; Cantero Santamaría, José I.; Baquero, José L.; De-Toro, Javier (Elsevier, 2019-01-10)[Abstract] Background: Treatment compliance with disease-modifying antirheumatic drugs (DMARD) is essential to achieve the therapeutic goals in rheumatoid arthritis (RA). However, despite the need for good compliance, there ... -
Analysis of the chondrogenic potential and secretome of mesenchymal stem cells derived from human umbilical cord stroma
Arufe, M.C.; Fuente, Alexandre de la; Mateos, Jesús; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J (Mary Ann Liebert, 2011-06-28)[Abstract] Mesenchymal stem cells (MSCs) from umbilical cord stroma were isolated by plastic adherence and characterized by flow cytometry, looking for cells positive for OCT3/4 and SSEA-4 as well as the classic MSC markers ... -
Anatomía del sistema digestivo
De-Toro, Javier; Fuentes Boquete, Isaac Manuel (Universidade da Coruña, 2005) -
Association between non-adherence behaviors, patients’ experience with healthcare and beliefs in medications: a survey of patients with different chronic conditions
Cea-Calvo, Luis; Marín-Jiménez, Ignacio; De-Toro, Javier; Fuster-RuizdeApodaca, María J.; Fernández, Gonzalo; Sánchez-Vega, Nuria; Orozco-Beltrán, Domingo (Taylor & Francis, 2019-10-15)[Abstract] Objective: The objective of the current work was to assess the frequency of non-adherence behaviors and potential association with patients' experience with healthcare and beliefs in medicines self-reported by ... -
Biomedical Applications of the Biopolymer Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV): Drug Encapsulation and Scaffold Fabrication
Rodríguez-Cendal, Ana Isabel; Gómez-Seoane, Iván; De-Toro, Javier; Fuentes Boquete, Isaac Manuel; Señarís, José; Díaz-Prado, Silvia (MDPI, 2023-07-19)[Abstract] Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) is a biodegradable and biocompatible biopolymer that has gained popularity in the field of biomedicine. This review provides an overview of recent advances and ... -
Blood RNA sequencing reveals immunological processes associated with the response to abatacept in rheumatoid arthritis.
Julià, Antonio; López Lasanta, María; Gómez, Antonio; Sanmartí, Raimon; Marras, Carlos; Pina Salvador, José Manuel; Romero Yuste, Susana; Veiga Cabello, Raúl María; Navarro, Pilar; Moragues Pastor, Carme; Martínez Pardo, Silvia; De-Toro, Javier; Sánchez, Amalia; Cerda, Dacia; Prada, Alejandro; Erra, Alba; Monfort, Jordi; Urruticoechea-Arana, Ana; Palau, Núria; Lastra, Raquel M.; Tortosa, Raúl; Pluma Sanjurjo, Andrea; Marsal, Sara (BMJ Journals, 2019-05-27) -
Bone marrow cells immunomagnetically selected for CD271+ antigen promote in vitro the repair of articular cartilage defects
Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; Gimeno-Longas, María José; Muíños-López, Emma; Díaz-Prado, Silvia; De-Toro, Javier; Blanco García, Francisco J (Mary Ann Liebert, 2011-03-22)[Abstract] Objective: The purposes of this project were to quantify the cells expressing the mesenchymal stem cell (MSC) marker CD271 in synovial membranes from human osteoarthritic (OA) and healthy joints, and to determine ... -
Cartilage tissue engineering: adult human mesenchymal stromal cells and collagen biomaterials
Sanjurjo-Rodríguez, Clara; Martínez Sánchez, A.H.; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; Buján, J.; De-Toro, Javier; Díaz-Prado, Silvia; Blanco García, Francisco J (Elsevier, 2014-03-20) -
CD105+-mesenchymal stem cells migrate into osteoarthritis joint: an animal model
Fernández-Pernas, Pablo; Rodríguez-Lesende, Iván; Fuente, Alexandre de la; Mateos, Jesús; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Arufe, M.C. (PLoS, 2017-11-30)[Abstract] Mesenchymal stem cells are being the focus of connective tissue technology and regenerative medicine, presenting a good choice cell source for improving old and well recognized techniques of cartilage defect ... -
Cell and Tissue Transplant Strategies for Joint Lesions
Fuentes Boquete, Isaac Manuel; Arufe, M.C.; Díaz-Prado, Silvia; Hermida Gómez, Tamara; De-Toro, Javier; Blanco García, Francisco J (Bentham Open, 2008-07-11)[Abstract] Articular cartilage lesions that do not disrupt the integrity of subchondral bone are not capable of spontaneous repair. The asymptomatic nature of these lesions leads to articular cartilage degeneration and ... -
Cell therapy and tissue engineering for cartilage repair
Piñeiro-Ramil, María; Castro Viñuelas, Rocío; Sanjurjo-Rodríguez, Clara; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Díaz-Prado, Silvia (IntechOpen, 2018-02-14)[Abstract] The integrity of the articular cartilage is necessary for the proper functioning of the diarthrodial joint. The self-repair capacity of this tissue is very limited and, currently, there is no effective treatment ... -
Chondrogenic potential of subpopulations of cells expressing mesenchymal stem cell markers derived from human synovial membranes
Arufe, M.C.; Fuente, Alexandre de la; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J (Wiley, 2010-07-21)[Abstract] In this study we analyzed the chondrogenic potential of subpopulations of mesenchymal stem cells (MSCs) derived from human synovial membranes enriched for CD73, CD106, and CD271 markers. Subpopulations of human ... -
Clinical profile, level of affection and therapeutic management of patients with osteoarthritis in primary care: the spanish multicenter study EVALÚA
Castaño Carou, Ana Isabel; Pita-Fernández, Salvador; Pértega-Díaz, Sonia; De-Toro, Javier (Elsevier, 2015-04-16)[Abstract] Objective. To determine the clinical profile, degree of involvement and management in patients with knee, hip or hand osteoarthritis. Methods. Observational study (health centres from 14 autonomous regions, n ... -
Different associations of intentional and non-intentional non-adherence behaviors with patient experience with healthcare and patient beliefs in medications: a survey of patients with chronic conditions
Cea-Calvo, Luis; Marín-Jiménez, Ignacio; De-Toro, Javier; Fuster-RuizdeApodaca, María J.; Fernández, Gonzalo; Sánchez-Vega, Nuria; Orozco-Beltrán, Domingo (Dove Press, 2020-12-14)[Abstract] Purpose: To investigate relationships between intentional and non-intentional non-adherence behaviors and patient experience with healthcare and beliefs in medications. Patients and methods: This is a post ... -
Differentiation of Synovial CD-105+ Human Mesenchymal Stem Cells into Chondrocyte-like Cells through Spheroid Formation
Arufe, M.C.; Fuente, Alexandre de la; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J (Wiley, 2009-06-18)[Abstract] Mesenchymal stem cells (MSCs) have the capacity to differentiate into several cell lineages, some of which can generate bone, cartilage, or adipose tissue. The presence of MSCs in the synovial membrane was ...
