Listar por autor "De-Toro, Javier"
Mostrando ítems 21-40 de 66
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Enhancing physical activity programs for diabetic patients at high and very high cardiovascular risk
Suárez-García, Patricia; Saavedra-García, Miguel A.; Soto-González, Alfonso; Fernández-Romero, Juan J.; De-Toro, Javier (Universitatea Nationala de Stiinta si Tehnologie Politehnica Bucaresti, 2023-10-31)[Abstract] This study aimed to identify the populations most susceptible to cardiovascular risks, aligning with the 2021 ESC guidelines. Additionally, this study aimed to evaluate statin prescriptions to determine suitable ... -
Establishment of human induced pluripotent stem cell-lines (IPSC) for in vitro modelling hand ostheoarthritis.
Castro Viñuelas, Rocío; Sanjurjo-Rodríguez, Clara; Piñeiro-Ramil, María; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Díaz-Prado, Silvia (BMJ Journals, 2019-05-27) -
Exploring the remission concept in rheumatoid arthritis with patients and rheumatologists: time for a new approach?
Acebes, Carlos; Andreu, José Luis; Balsa, Alejandro; Batlle, Enrique; De-Toro, Javier; García Llorente, Francisco; Hernández, María Victoria; Fernández-Gutiérrez, Benjamín; Hidalgo-Calleja, Cristina; Mayordomo, Lucía; Naredo, Esperanza; Narváez, Francisco Javier; Ortiz, Ana M.; Pablos, José Luis; Pérez-Sandoval, Trinidad; Rodríguez-Lozano, Carlos; Sánchez-Pernaute, Olga; Usón, Jacqueline; Negrón, José Bernardo; Loza, Estíbaliz; Carmona, Loreto; Gómez Castro, Susana; Montoro Álvarez, María (Clinical and Experimental Rheumatology, 2017-09)[Abstract] Objectives: To explore the remission concept in rheumatoid arthritis (RA) and to compare remission definitions and related concepts between rheumatologists and patients with the purpose of identifying ... -
Generation and characterization of human induced pluripotent stem cells (iPSCs) from hand osteoarthritis patient-derived fibroblasts
Castro Viñuelas, Rocío; Sanjurjo-Rodríguez, Clara; Piñeiro-Ramil, María; Hermida Gómez, Tamara; Rodríguez-Fernández, Silvia; Oreiro, Natividad; De-Toro, Javier; Fuentes Boquete, Isaac Manuel; Blanco García, Francisco J; Díaz-Prado, Silvia (Nature Research, 2020-03-06)[Abstract] Knowledge and research results about hand osteoarthritis (hOA) are limited due to the lack of samples and animal models of the disease. Here, we report the generation of two induced pluripotent stem cell ... -
Generation of osteoarthritic mesenchymal stromal cell lines.
Piñeiro-Ramil, María; Castro Viñuelas, Rocío; Sanjurjo-Rodríguez, Clara; Rodríguez-Fernández, Silvia; Hermida Gómez, Tamara; De-Toro, Javier; Blanco García, Francisco J; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia (BMJ Journals, 2019-05-27) -
Generation of osteoarthritis and healthy mesenchymal cell lines for research on regenerative medicine for osteoarthritis
Piñeiro-Ramil, María; Castro Viñuelas, Rocío; Sanjurjo-Rodríguez, Clara; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Díaz-Prado, Silvia (2018-04)[Purpose] Bone-marrow mesenchymal stem cells (BM-MSCs) are multipotent self-renewal adult cells with potential to regenerate the damaged tissues in degenerative diseases such as osteoarthritis (OA). Nevertheless, research ... -
Healthcare experience among patients with type 2 diabetes: A cross-sectional survey using the IEXPAC tool
Orozco-Beltrán, Domingo; Artola-Menéndez, Sara; Hormigo-Pozo, Antonio; Cararach-Salami, Daniel; Alonso-Jerez, José Luis; Álvaro-Grande, Epifanio; Villalibre-Arias, Covadonga; De-Toro, Javier; Galindo-Puerto, María José; Marín-Jiménez, Ignacio; Gómez-García, Antón; Ledesma-Rodríguez, Rocío; Fernández, Gonzalo; Ferreira de Campos, Karine (Wiley, 2021-02-15)[Abstract] Aim: To assess the experience with health care among patients with type 2 diabetes (T2DM) and to evaluate patients' demographic variables and healthcare-related characteristics which may affect their ... -
Healthcare experience and their relationship with demographic, disease and healthcare-related variables: a cross-sectional survey of patients with chronic diseases using the IEXPAC scale.
Orozco-Beltrán, Domingo; De-Toro, Javier; Galindo, María J.; Marín-Jiménez, Ignacio; Casellas, Francesc; Fuster-RuizdeApodaca, María J.; García-Vivar, María L.; Hormigo-Pozo, Antonio; Guilabert, Mercedes; Sánchez-Vega, Nuria; Fernández, Gonzalo; Cea-Calvo, Luis (Springer, 2018-11-15)[Abstract] BACKGROUND: Patient experience is acknowledged as a principal aspect of quality healthcare delivery, and it has implications with regard to outcomes. OBJECTIVES: Our objective was to evaluate the healthcare ... -
Hemophagocytic syndrome in patients from SLE Registry from the Spanish Society of Rheumatology (RELESSER)
Lois Iglesias, Ana J.; Rua Figueroa, I.; De-Toro, Javier; Zea-Mendoza, A.; López-Longo, J.; Calvo, J.; Galindo, M.; Uriarte-Isacelaya, E.; Pego-Reigosa, J. (BMJ, 2017) -
High-Throughput Screen Detects Calcium Signaling Dysfunction in Hutchinson-Gilford Progeria Syndrome
Fafián Labora, Juan Antonio; Morente López, Miriam; De-Toro, Javier; Arufe, M.C. (MDPI, 2021-07-07)[Abstract] Hutchinson–Gilford progeria syndrome (HGPS) is a deadly childhood disorder, which is considered a very rare disease. It is caused by an autosomal dominant mutation on the LMNA gene, and it is characterized by ... -
Higher synovial immunohistochemistry reactivity of IL-17A, Dkk1, and TGF-β1 in patients with early psoriatic arthritis and rheumatoid arthritis could predict the use of biologics
Pinto-Tasende, José A.; Fernández-Moreno, Mercedes; Rego-Pérez, Ignacio; Fernández-López, J. Carlos; Oreiro, Natividad; De-Toro, Javier; Blanco García, Francisco J (MDPI, 2024-04-08)[Abstract] Background: Delay in diagnosis and therapy in patients with arthritis commonly leads to progressive articular damage. The study aimed to investigate the immunohistochemical reactivity of synovial cytokines ... -
Human amniotic membrane as an alternative source of stem cells for regenerative medicine
Díaz-Prado, Silvia; Muiños-López, Emma; Hermida Gómez, Tamara; Cicione, Claudia; Rendal Vázquez, María Esther; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J (Elsevier, 2011-02-19)[Abstract] The human amniotic membrane (HAM) is a highly abundant and readily available tissue. This amniotic tissue has considerable advantageous characteristics to be considered as an attractive material in the field of ... -
Human amniotic membrane: a potential tissue and cell source for cell therapy and regenerative medicine
Díaz-Prado, Silvia; Muíños-López, Emma; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J (Springer, 2013)[Abstract] The human amniotic membrane (HAM) is the innermost membrane surrounding the fetus. HAM is a highly abundant and readily available tissue that is becoming appreciated as an alternative to adult bone marrow ... -
Human amniotic mesenchymal stromal cells as favorable source for cartilage repair
Muiños-López, Emma; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Díaz-Prado, Silvia (Mary Ann Liebert, 2017-01-10)[Abstract] Introduction: Localized trauma-derived breakdown of the hyaline articular cartilage may progress toward osteoarthritis, a degenerative condition characterized by total loss of articular cartilage and joint ... -
Human cartilage engineering in an in vitro repair model using collagen scaffolds and mesenchymal stromal cells
Sanjurjo-Rodríguez, Clara; Castro Viñuelas, Rocío; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Díaz-Prado, Silvia (Ivyspring, 2017-09-28)[Abstract] The purpose of this study was to investigate cartilage repair of in vitro lesion models using human bone marrow mesenchymal stromal cells (hBMSCs) with different collagen (Col) scaffolds. Lesions were made ... -
Identification of patients at risk of non-adherence to oral antirheumatic drugs in rheumatoid arthritis using the Compliance Questionnaire in Rheumatology: an ARCO sub-study
Marras, Carlos; Monteagudo, Indalecio; Salvador, Georgina; De-Toro, Javier; Escudero, Alejandro; Alegre-Sancho, Juan J.; Raya, Enrique; Ortiz, Ana; Carmona, Loreto; Mestre, Yvonne; Cea-Calvo, Luis; Calvo-Alén, Jaime (Springer, 2017-05-17)[Abstract] The ARCO study (Study on Adherence of Rheumatoid Arthritis patients to SubCutaneous and Oral Drugs), a multicenter, non-interventional retrospective study, was primarily designed to assess the percentage of ... -
Induced pluripotent stem cells for cartilage repair: current status and future perspectives
Castro Viñuelas, Rocío; Sanjurjo-Rodríguez, Clara; Piñeiro-Ramil, María; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Díaz-Prado, Silvia (AO Research Institute Davos, 2018-09-11)[Abstract] The establishment of cartilage regenerative medicine is an important clinical issue, but the search for cell sources able to restore cartilage integrity proves to be challenging. Human mesenchymal stromal cells ... -
Influence of age on rat bone-marrow mesenchymal stem cells potential
Fafián Labora, Juan Antonio; Fernández-Pernas, Pablo; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Oreiro, Natividad; Sangiao-Alvarellos, Susana; Mateos, Jesús; Arufe, M.C. (Nature, 2015-11-19)[Abstract] Mesenchymal stem cells promising role in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor age. Six age groups from bone ... -
Influence of mesenchymal stem cell-derived extracellular vesicles in vitro and their tole in ageing
Fafián Labora, Juan Antonio; Morente-López, Miriam; Sánchez-Dopico, María José; Arntz, O.J.; Van de Loo, F.J.; De-Toro, Javier; Arufe, M.C. (Springer Nature, 2020-01-03)[Abstract] Introduction: This study assessed whether mesenchymal stem cell (MSC)-derived extracellular vesicles influenced ageing and pluripotency markers in cell cultures where they are added. Methods: MSC-derived ... -
Is myofascial release therapy cost-effective when compared with manual therapy to treat workers’ mechanical neck pains?
Rodríguez Fuentes, Iván; De-Toro, Javier; Rodríguez Fuentes, Gustavo; Oliveira, Iris Machado de; Meijide-Faílde, Rosa; Fuentes Boquete, Isaac Manuel (Elsevier, 2020-09-12)[Abstract] Objective: The aim of this study was to do a cost-benefit analysis of myofascial release therapy (MRT) compared to manual therapy (MT) for treating occupational mechanical neck pain. Methods: Variables regarding ...