Browsing by Author "Mena, Álvaro"
Now showing items 21-33 of 33
-
Neoplasias en pacientes con infección por VIH: estudio descriptivo de 129 casos en el período 1993-2010
Meijide, Héctor; Mena, Álvaro; Pernas, Berta; Castro-Iglesias, Ángeles; López, Soledad; Vázquez-Rodríguez, Pilar; Bello, Laura; Baliñas, Josefa; Rodríguez-Martínez, Guillermo; Pedreira, José D. (Sociedad Chilena de Infectología, 2013)[Resumen] Introducción: Uno de los problemas asociados a la infección por VIH es el desarrollo de neoplasias. La incidencia y espectro de los distintos cánceres se ha visto modificada con la incorporación del tratamiento ... -
Plasma mitochondrial DNA levels are inversely associated with HIV-RNA levels and directly with CD4 counts: potential role as a biomarker of HIV replication
Pernas, Berta; Rego-Pérez, Ignacio; Tabernilla, Andrés; Balboa-Barreiro, Vanesa; Relaño, Sara; Grandal, Marta; Crespo, Manuel; Mena, Álvaro; Castro-Iglesias, Ángeles; Blanco García, Francisco J; Poveda, Eva (Oxford, 2017-08-31)[Abstract] Objectives. To evaluate plasma mitochondrial DNA (mtDNA) levels among HIV-infected patients and its potential role as a biomarker of residual viral replication. Methods. HIV-infected patients on follow-up at a ... -
Predictors of hepatitis C treatment failure after using direct-acting antivirals in people living with human immunodeficiency virus
Cachay, Edward R.; Mena, Álvaro; Morano, Luis; Benitez, Laura; Maida, Ivana; Ballard, Craig; Hill, Lucas; Torriani, Francesca; Castro-Iglesias, Ángeles; Dore, Elena; Castro, Sheila; Mendoza Fernández, Carmen de; Soriano, Vicente; Mathews, Wm. C. (Oxford, 2019-02-11)[Abstract] Background. Little is known about the influence of ongoing barriers to care in the persistence of hepatitis C virus (HCV) viremia after treatment with direct-acting antivirals (DAAs) among people living with ... -
Prevalence of NS5A resistance associated substitutions in patients with hepatitis C virus genotypes 1a and 3: Impact on current therapeutic strategies
Grandal, Marta; Pernas, Berta; Tabernilla, Andrés; Mariño, Ana; Álvarez, Hortensia; Valcarce, Nieves; Mena, Álvaro; Castro-Iglesias, Ángeles; Pérez, Ana B.; Delgado, Manuel; Poveda, Eva (Wiley, 2018-02-10)[Abstract] The presence of resistance‐associated substitutions (RASs) at NS5A region might compromise the efficacy of Direct Acting Antiviral agents (DAAs). HCV resistance at NS5A region is mainly focused on patients with ... -
Real life experience with direct-acting antivirals agents against hepatitis C infection in elderly patients
Rodríguez-Osorio, Iria; Cid-Silva, Purificación; Morano, Luis; Castro-Iglesias, Ángeles; Suárez, Marta; Delgado, Manuel; Margusino-Framiñán, Luis; Meijide, Héctor; Pernas, Berta; Tabernilla, Andrés; Pedreira, José D.; Mena, Álvaro; Poveda, Eva (Elsevier, 2017-01-18)[Abstract] Background. New direct-acting antivirals agents (DAAs) are very safe and well tolerated. Objectives. The purpose of this study is to analyse the efficacy and safety of DAAs in elderly patients, who have ... -
Seroprevalence of HCV and HIV infections by year of birth in Spain: impact of US CDC and USPSTF recommendations for HCV and HIV testing
Mena, Álvaro; Moldes, Luz; Meijide, Héctor; Cañizares, Angelina; Castro-Iglesias, Ángeles; Delgado, Manuel; Pértega-Díaz, Sonia; Pedreira, José D.; Bou, Germán; Poveda, Eva (PLoS ONE, 2014-12-01) -
Similar plasma lipidomic profile in people living with HIV treated with a darunavir-based or an integrase inhibitor-based antiretroviral therapy
Mena, Álvaro; Clavero, Elvira; Díaz-Díaz, José Luis; Castro-Iglesias, Ángeles (Nature, 2019-11-20)[Abstract] Cardiovascular disease is an important cause of morbidity and mortality in people living with HIV (PLWH), who commonly experience lipid disturbances. The aim of this study was to determine whether the plasma ... -
Teleconsultation for the pharmaceutical care of HIV outpatients in receipt of home antiretrovirals delivery: clinical, economic, and patient-perceived quality analysis
Margusino-Framiñán, Luis; Cid-Silva, Purificación; Castro-Iglesias, Ángeles; Mena, Álvaro; Rodríguez-Osorio, Iria; Pernas Souto, Berta; Vázquez-Rodríguez, Pilar; López-Calvo, Soledad; Martín-Herranz, Isabel (Mary Ann Liebert, 2018-07-19)[Abstract] Background/Introduction: Pharmacist teleconsultations, combined with home drug delivery or mail-order pharmacy (MOP), can help hospital outpatients with difficulties accessing treatment. The objectives of this ... -
Treatment with tenofovir alafenamide fumarate worsens the lipid profile of HIV‐infected patients versus treatment with tenofovir disoproxil fumarate, each coformulated with elvitegravir, cobicistat, and emtricitabine
Cid-Silva, Purificación; Fernández-Bargiela, Noelia; Margusino-Framiñán, Luis; Balboa-Barreiro, Vanesa; Mena, Álvaro; López-Calvo, Soledad; Vázquez-Rodríguez, Pilar; Martín-Herranz, Isabel; Míguez-Rey, Martín; Poveda, Eva; Castro-Iglesias, Ángeles (Wiley, 2018-11-02)[Abstract] Two elvitegravir/cobicistat‐based therapies combined with emtricitabine/tenofovir disoproxil fumarate (EVG/c/FTC/TDF) or emtricitabine/tenofovir alafenamide fumarate (EVG/c/FTC/TAF) are currently available for ... -
Trends in hospital admissions, re-admissions, and in-hospital mortality among HIV-infected patients between 1993 and 2013: impact of hepatitis C co-infection
Meijide, Héctor; Mena, Álvaro; Rodríguez-Osorio, Iria; Pértega-Díaz, Sonia; Castro-Iglesias, Ángeles; Rodríguez-Martínez, Guillermo; Pedreira, José D.; Poveda, Eva (Elsevier, 2017-02-15)[Abstract] Background. New patterns in epidemiological characteristics of people living with HIV infection (PLWH) and the introduction of Highly Active Antiretroviral Therapy (HAART) have changed the profile of hospital ... -
Trends on epidemiological, virological, and clinical features among newly diagnosed HIV-1 persons in Northwest Spain over the last 10 years
Pernas, Berta; Mena, Álvaro; Cañizares, Angelina; Grandal, Marta; Castro-Iglesias, Ángeles; Pértega-Díaz, Sonia; Pedreira, José D.; Poveda, Eva (Wiley, 2015-03-16)[Abstract] To describe temporal trend and characteristics of newly HIV-diagnosed patients in a medical care area in Northwest Spain over the last 10 years. All newly diagnosed patients for HIV-infection from 2004 to 2013 ... -
Update on hepatitis C virus resistance to direct-acting antiviral agents
Poveda, Eva; Wyles, David L.; Mena, Álvaro; Pedreira, José D.; Castro-Iglesias, Ángeles; Cachay, Edward (Elsevier, 2014-06-06)[Abstract] Resistance to direct-acting antiviral (DAA) agents against hepatitis C virus (HCV) infection is driven by the selection of mutations at different positions in the NS3 protease, NS5B polymerase and NS5A proteins. ... -
Utilidad de la elastografía hepática (Fibroscan) en la caracterización y seguimiento de pacientes con hepatitis crónica B
Mena, Álvaro (2015)[Resumen] Objetivos: el objetivo principal del presente estudio es determinar la prevalencia de fibrosis avanzada y definir los factores asociados a la misma, medida mediante EH, en pacientes con HCB clasificados como ...