• Single nucleotide polymorphism genes and mitochondrial DNA haplogroups as biomarkers for early prediction of knee osteoarthritis structural progressors: use of supervised machine learning classifiers 

      Bonakdari, Hossein; Petellier, Jean-Pierre; Blanco García, Francisco J; Rego-Pérez, Ignacio; Durán-Sotuela, Alejandro; Aitken, Dawn; Jones, Graeme; Cicuttini, Flavia; Jamshidi, Afshin; Abram, François; Martel-Pelletier, Johanne (BioMed Central, 2022-09-12)
      [Abstract] Background. Knee osteoarthritis is the most prevalent chronic musculoskeletal debilitating disease. Current treatments are only symptomatic, and to improve this, we need a robust prediction model to stratify ...
    • Specific premature epigenetic aging of cartilage in osteoarthritis 

      Vidal-Bravo, Laura; López-Golán, Yolanda; Mera-Varela, Antonio; Rego-Pérez, Ignacio; Horvath, Steve; Zhang, Yuhua; Real, Álvaro del; Zhai, Guangju; Blanco García, Francisco J; Riancho, José A.; Gómez-Reino, Juan J.; González, Antonio (Impact Journals, 2016-09-28)
      [Abstract] Osteoarthritis (OA) is a disease affecting multiple tissues of the joints in the elderly, but most notably articular cartilage. Premature biological aging has been described in this tissue and in blood cells, ...
    • What did we learn from 'omics' studies in osteoarthritis 

      Ruiz-Romero, Cristina; Rego-Pérez, Ignacio; Blanco García, Francisco J (Wolters Kluwer, 2018-01-01)
      [Abstract] Purpose of review: 'Omics' technologies developed for the massive analysis of the major biologically relevant molecules (genes, proteins, metabolites) have been applied to the study of osteoarthritis (OA) for ...