Listar Grupo Fisiopatoloxía Endócrina, Nutricional e Médica (FENM) por título

Mostrando ítems 68-87 de 109

    • Maternal and perinatal outcomes after bariatric surgery: a spanish multicenter study 

      González, Irene; Rubio, Miguel A.; Cordido, Fernando; Bretón, Irene; Morales, María J.; Vilarrasa, Nuria; Monereo, Susana; Lecube, Albert; Caixás, Assumpta; Vinagre, Irene; Goday, Albert; García Luna, Pedro Pablo (Springer, 2014-08-15)
      [Abstract] Background. Bariatric surgery (BS) has become more frequent among women of child-bearing age. Data regarding the underlying maternal and perinatal risks are scarce. The objective of this nationwide study is to ...

    • Metabolic Recovery After Weight Loss Surgery Is Reflected in Serum microRNAs 

      Sangiao-Alvarellos, Susana; Theofilatos, Konstantinos; Barwari, Temo; Gutmann, Clemens; Takov, Kaloyan; Singh, Bhawana; Juiz-Valiña, Paula; Varela-Rodríguez, Bárbara María; Outeiriño-Blanco, Elena; Duregotti, Elisa; Zampetaki, Anna; Lunger, Lukas; Ebenbichler, Christoph; Tilg, Herbert; García-Brao, María Jesús; Willeit, Peter; Mena, Enrique; Kiechl, Stefan; Cordido, Fernando; Mayr, Manuel (BMJ Publishing Group, 2020-10-01)
      [Abstract] INTRODUCTION: Bariatric surgery offers the most effective treatment for obesity, ameliorating or even reverting associated metabolic disorders, such as type 2 diabetes. We sought to determine the effects of ...

    • MicroARN circulantes en sangre de pacientes con cáncer de próstata 

      Medina Villaamil, Vanessa; Martínez-Breijo, S.; Portela-Pereira, P.; Quindós-Varela, María; Santamarina, Isabel; Antón-Aparicio, Luis M.; Gómez Veiga, Francisco (Elsevier, 2014)
      [Resumen] Introducción. Los microARN (miARN) son ARN reguladores de pequeño tamaño que no codifican para proteínas. La detección de células tumorales circulantes (CTC) proporcionaría información diagnóstica y pronóstica ...

    • MiR-19 family impairs adipogenesis by the downregulation of the PPARγ transcriptional network 

      Juiz-Valiña, Paula; Varela-Rodríguez, Bárbara María; Outeiriño-Blanco, Elena; García-Brao, María Jesús; Mena, Enrique; Cordido, Fernando; Sangiao-Alvarellos, Susana (MDPI, 2022-12-13)
      [Abstract] microRNAs (miRNAs) are a class of small endogenous RNA that play pivotal roles in both the differentiation and function of adipocytes during the development of obesity. Despite this, only a few miRNA families ...

    • Mortality in acromegaly diagnosed in older individuals in Spain is higher in women compared to the general spanish population 

      Biagetti, Betina; Iglesias, Pedro; Villar-Taibo, Rocío; Moure, María-Dolores; Paja, Miguel; Araújo-Castro, Marta; Ares, Jessica; Álvarez-Escola, Cristina; Vicente, Almudena; Álvarez Guivernau, Èlia; Novoa-Testa, Iria; Guerrero Pérez, Fernando; Cámara, Rosa; Lecumberri, Beatriz; García Gómez, Carlos; Bernebéu, Ignacio; Manjón, Laura; Gaztambide, Sonia; Cordido, Fernando; Webb, Susan M.; Menéndez-Torre, Edelmiro Luis; Díez, Juan J.; Simó, Rafael; Puig-Domingo, Manel (Oxford Academic, 2023-03-14)
      [Abstract] Context: There are no data on mortality of acromegaly diagnosed in older individuals. Objective: This work aimed to compare clinical characteristics, growth hormone-related comorbidities, therapeutic approaches, ...

    • Multiple biomarker tissue arrays: a computational approach to identifying protein-protein interactions in the EGFR/ERK signalling pathway 

      Medina Villaamil, Vanessa; Aparicio Gallego, Guadalupe; Valladares-Ayerbes, Manuel; Santamarina, Isabel; Antón-Aparicio, Luis M. (BioMed Central, 2012-09-01)
      [Abstract] Background. Many studies have demonstrated genetic and environmental factors that lead to renal cell carcinoma (RCC) and that occur during a protracted period of tumourigenesis. It appears suitable to identify ...

    • Non-functioning pituitary adenoma underwent surgery: a multicenter retrospective study over the last four decades (1977–2015) 

      Iglesias, Pedro; Arcano, Karina; Triviño, Vanessa; García-Sancho, Paula; Díez, Juan José; Cordido, Fernando; Villabona, Carles (Elsevier, 2017-04-04)
      [Abstract] Objective. To assess clinical features, diagnostic procedures, therapies and outcomes in patients with clinically non-functioning pituitary adenomas (NFPAs) surgically treated over the last four decades. Design ...

    • Novel potential predictive markers of sunitinib outcomes in long-term responders versus primary refractory patients with metastatic clear-cell renal cell carcinoma 

      Puente, Javier; Lainez, Nuria; Dueñas, Marta; Méndez-Vidal, María José; Esteban, Emilio; Castellano, Daniel; Martínez-Fernández, Mónica; Basterretxea, Laura; Juan-Fita, María José; Antón-Aparicio, Luis M.; León, Luis; Lambea, Julio; Pérez-Valderrama, Begoña; Vázquez, Sergio; Suárez, Cristina; García del Muro, Xavier; Gallardo, Enrique; Maroto, José Pablo; Samaniego, M. Luz; Suárez-Paniagua, Beatriz; Sanz, Julián; Paramio, Jesús M. (Impact Journals, 2017-03-23)
      [Abstract] Background: Several potential predictive markers of efficacy of targeted agents in patients with metastatic renal cell carcinoma (mRCC) have been identified. Interindividual heterogeneity warrants further ...

    • Obesity, adipose tissue, inflammation and update on obesity management 

      Cordido, Fernando; García-Mayor, Ricardo V.; Larranaga, Alejandra (Symbiosis, 2014-11-12)
      [Abstract] Obesity is a serious, common and growing problem. Obesity can be defined as an excess of body fat. Its clinical management is complex and frequently unsuccessful. It has only recently been regarded as a chronic ...

    • Oral glucose-stimulated growth hormone (GH) test in adult GH deficiency patients and controls: potential utility of a novel test 

      Pena-Bello, Lara; Seoane-Pillado, Teresa; Sangiao-Alvarellos, Susana; Outeiriño-Blanco, Elena; Varela-Rodríguez, Bárbara María; Juiz-Valiña, Paula; Cordido, María; Cordido, Fernando (Elsevier para European Federation of Internal Medicine, 2017-06-09)
      [Abstract] Context. The diagnosis of adult GH deficiency requires confirmation with a GH stimulation test. Oral glucose (OG) administration affects GH secretion, initially decreasing and subsequently stimulating GH ...

    • Patología tiroidea en atención primaria 

      Núñez Vázquez, Ángel; Cordido, Fernando; Gómez Gómez, Natalia; Lois Rodríguez, Marta; Cordido, María; Louro González, Arturo (Elsevier, 2016-12)

    • Peritoneal protein transport during the baseline peritoneal equilibration test is an accurate predictor of the outcome of peritoneal dialysis patients 

      Pérez-Fontán, Miguel; Rodríguez Carmona, Ana; Barreda, D.; López-Muñiz, Andrés; Blanco-Castro, N.; García Falcón, María Teresa (Karger, 2010)
      [Abstract] Background: Peritoneal protein excretion (PPE) is a potential marker of the outcome in peritoneal dialysis (PD) patients. Method: Observational study of a cohort of 269 patients starting PD in a single unit. ...

    • Peritoneal water transport characteristics of diabetic patients undergoing peritoneal dialysis: a longitudinal study 

      Fernandes, Ana; Ribera-Sánchez, Roi; Rodríguez Carmona, Ana; López-Iglesias, Antía; Leite-Costa, Natacha; Pérez-Fontán, Miguel (Karger, 2017-06-21)
      [Abstract] Background: Volume overload is frequent in diabetics undergoing peritoneal dialysis (PD), and may play a significant role in the excess mortality observed in these patients. The characteristics of peritoneal ...

    • Perturbation of hypothalamic MicroRNA expression patterns in male rats after metabolic distress: impact of obesity and conditions of negative energy balance 

      Sangiao-Alvarellos, Susana; Pena-Bello, Lara; Manfredi-Lozano, María; Tena-Sempere, Manuel; Cordido, Fernando (Endocrine Society, 2014-02-11)
      [Abstract] The hypothalamus plays a crucial role in body weight homeostasis through an intricate network of neuronal circuits that are under the precise regulation of peripheral hormones and central transmitters. Although ...

    • Phase II Randomized Study of Figitumumab plus Docetaxel and Docetaxel Alone with Crossover for Metastatic Castration-Resistant Prostate Cancer 

      De Bono, Johann S.; Piulats, Josep María; Pandha, Hardev S.; Petrylak, Daniel P.; Saad, Fred; Antón-Aparicio, Luis M.; Sandhu, Shahneen K.; Fong, Peter; Gillessen, Silke; Hudes, Gary R.; Wang, Tao; Scranton, Judith; Pollak, Michael N. (American Association for Cancer Research, 2014-02-17)
      [Abstract] PURPOSE: Figitumumab is a human IgG2 monoclonal antibody targeting insulin-like growth factor 1 receptor (IGF-1R), with antitumor activity in prostate cancer. This phase II trial randomized chemotherapy-naïve ...

    • Place of preoperative treatment of acromegaly with somatostatin analog on surgical outcome: a systematic review and meta-analysis 

      Pita-Gutiérrez, Francisco; Pértega-Díaz, Sonia; Pita-Fernández, Salvador; Pena, Lara; Lugo, Gloria; Sangiao-Alvarellos, Susana; Cordido, Fernando (PLoS ONE, 2013-04-25)
      [Abstract] Context. Transsphenoidal neurosurgery is the accepted first-line treatment of acromegaly in the majority of patients. Previous studies addressing preoperative somatostatin analog (SSA) treatment and subsequent ...

    • Potential role of sugar transporters in cancer and their relationship with anticancer therapy 

      Blanco, Moisés; Figueroa, Angélica; Grande Pulido, Enrique; García Campelo, Rosario; Antón-Aparicio, Luis M. (Hindawi, 2010-06-20)
      [Abstract] Sugars, primarily glucose and fructose, are the main energy source of cells. Because of their hydrophilic nature, cells use a number of transporter proteins to introduce sugars through their plasma membrane. ...

    • Prevalence, clinical features, and natural history of incidental clinically non-functioning pituitary adenomas 

      Iglesias, Pedro; Arcano, Karina; Triviño, Vanessa; García-Sancho, Paula; Díez, Juan José; Villabona, Carles; Cordido, Fernando (Thieme, 2017-07-31)
      [Abstract] The objective of the study was to assess the prevalence and clinical features of incidentally discovered clinically non-functioning pituitary adenoma (CNFPA) and to analyze its natural history. A multicenter ...

    • Prognostic impact of disseminated tumor cells and microRNA-17-92 cluster deregulation in gastrointestinal cancer 

      Valladares-Ayerbes, Manuel; Blanco, Moisés; Haz, Mar; Medina, Vanessa; Iglesias-Díaz, Pilar; Lorenzo-Patiño, María J.; Reboredo, Margarita; Santamarina, Isabel; Figueroa, Angélica; Antón-Aparicio, Luis M.; Calvo, Lourdes (Spandidos, 2011-07-04)
      [Abstract] The presence of tumor cells in the bone marrow (BM) could be relevant to identifying high risk of disease progression and death in gastrointestinal cancer. However, the molecular profile associated with disseminated ...

    • Prostate carcinoma and stem cells 

      Antón-Aparicio, Luis M.; Cassinello Espinosa, J.; García Campelo, Rosario; Gómez Veiga, Francisco; Díaz-Prado, Silvia; Aparicio Gallego, Guadalupe (Springer, 2007-02)
      [Abstract] Stem cells, as classically defined, are cells with a capacity to self-renew and to generate daughter cells that can differentiate down several cell lineages to form all of the cell types that are found in the ...