Listar Grupo Fisiopatoloxía Endócrina, Nutricional e Médica (FENM) por título

Mostrando ítems 59-78 de 109

    • How a bottom-up multi-stakeholder initiative helped transform the renal replacement therapy landscape in Spain 

      Selgas, Rafael; Rodríguez, Laura; Julián, Juan Carlos; Remón, César; Prieto-Velasco, Mario; Pérez-Contreras, Javier; Pérez-Fontán, Miguel (Springer, 2017-03-06)
      [Abstract] Healthcare reforms aim to change certain parts of the health system to improve quality of care, access, or financial sustainability. Traditionally, healthcare reform is understood as an action undertaken by a ...

    • Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3 

      Heras, Violeta; Sangiao-Alvarellos, Susana; Manfredi-Lozano, María; Sánchez-Tapia, María J.; Ruiz-Pino, Francisco; Roa, Juan; Lara-Chica, Maribel; Morrugares-Carmona, Rosario; Jouy, Nathalie; Abreu, Ana P.; Prevot, Vincent; Belsham, Denise; Vázquez, María J.; Calzado, Marco A.; Pinilla, Leonor; Gaytán, Francisco; Latronico, Ana C.; Kaiser, Ursula B.; Castellano, Juan M.; Tena-Sempere, Manuel (Public Library of Science (PLoS), 2019-11-07)
      [Abstract] Mkrn3, the maternally imprinted gene encoding the makorin RING-finger protein-3, has recently emerged as putative pubertal repressor, as evidenced by central precocity caused by MKRN3 mutations in humans; ...

    • Identification of targets for prevention of peritoneal catheter tunnel and exit-site infections in low incidence settings 

      Santos, Clara; Pérez-Fontán, Miguel; Rodríguez-Carmona, Ana; Calvo-Rodríguez, María; López-Muñiz, Andrés; López-Calviño, Beatriz; García Falcón, María Teresa (SAGE, 2016-01-01)
      [Abstract] ♦ Background: Peritoneal catheter tunnel and exit-site infection (TESI) complicates the clinical course of peritoneal dialysis (PD) patients. Adherence to recommendations for catheter insertion, exit-site care, ...

    • Influence of Age on Rat Bone-Marrow Mesenchymal Stem Cells Potential 

      Fafián Labora, Juan Antonio; Fernández-Pernas, Pablo; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Oreiro, Natividad; Sangiao-Alvarellos, Susana; Mateos, Jesús; Arufe, M.C. (Nature, 2015-11-19)
      [Abstract] Mesenchymal stem cells promising role in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor age. Six age groups from bone ...

    • Influence of ghrelin and growth hormone deficiency on AMP-activated protein kinase and hypothalamic lipid metabolism 

      Sangiao-Alvarellos, Susana; Varela, Luis; Vázquez, María J.; Boit, K. Da; Saha, A.K.; Cordido, Fernando; Diéguez, Carlos; López, Miguel (Wiley, 2010-03-08)
      [Abstract] Current evidence demonstrates that the stomach-derived hormone ghrelin, a potent growth hormone (GH) secretagogue, promotes feeding through a mechanism involving the short-term activation of hypothalamic ...

    • Influence of peritoneal residual volume on the results of the peritoneal equilibration test: prospective study 

      Falcao, Luis; García Gago, Leticia; Astudillo, Daniela; Rodríguez-Magariños, Catuxa; Blanco Pardo, Marta; Rodríguez-Carmona, Ana; Pérez-Fontán, Miguel (Sociedad Española de Nefrología, 2023-03)
      [Abstract] Background: Categorization of the capacity of ultrafiltration during a peritoneal equilibration test (PET) is a usual step during the monitoring of peritoneal transport characteristics of Peritoneal Dialysis ...

    • Inhibition of gastric acid secretion by H2 receptor antagonists associates a definite risk of enteric peritonitis and infectious mortality in patients treated with peritoneal dialysis 

      Pérez-Fontán, Miguel; Machado Lopes, Daniela; García Enríquez, Alba; López-Calviño, Beatriz; López-Muñiz, Andrés; García Falcón, María Teresa; Rodríguez-Carmona, Ana (PLOS, 2016-02-12)
      [Abstract] Background. Evidences linking treatment with inhibitors of gastric acid secretion (IGAS) and an increased risk of serious infections are inconclusive, both in the population at large and in the particular case ...

    • Involvement of mitochondrial dysfunction in the inflammatory response in human mesothelial cells from peritoneal dialysis effluent 

      Ramil-Gómez, Olalla; López-Pardo, Mirian; Fernández-Rodríguez, Jennifer Adriana; Rodríguez-Carmona, Ana; Pérez-López, Teresa; Vaamonde-García, Carlos; Pérez-Fontán, Miguel; López-Armada, María José (MDPI, 2022-11-04)
      [Abstract] Recent studies have related mitochondrial impairment with peritoneal membrane damage during peritoneal dialysis (PD) therapy. Here, we assessed the involvement of mitochondrial dysfunction in the inflammatory ...

    • Long-Term Trends in the Incidence of Peritoneal Dialysis-Related Peritonitis Disclose an Increasing Relevance of Streptococcal Infections: A Longitudinal Study 

      Santos, Joana Eugénio; Rodríguez-Magariños, Catuxa; García Gago, L.; Astudillo-Jarrín, Daniela; Pértega-Díaz, Sonia; Rodríguez-Carmona, Ana; García Falcón, María Teresa; Pérez-Fontán, Miguel (Public Library of Science (PLoS), 2020-12-21)
      [Abstract} Background. The selective impact of strategies for prevention of PD-related peritonitis (PDrP) may have modified, in the long term, the causal spectrum, clinical presentation and outcomes of these ...

    • Maternal and perinatal outcomes after bariatric surgery: a spanish multicenter study 

      González, Irene; Rubio, Miguel A.; Cordido, Fernando; Bretón, Irene; Morales, María J.; Vilarrasa, Nuria; Monereo, Susana; Lecube, Albert; Caixás, Assumpta; Vinagre, Irene; Goday, Albert; García Luna, Pedro Pablo (Springer, 2014-08-15)
      [Abstract] Background. Bariatric surgery (BS) has become more frequent among women of child-bearing age. Data regarding the underlying maternal and perinatal risks are scarce. The objective of this nationwide study is to ...

    • Metabolic Recovery After Weight Loss Surgery Is Reflected in Serum microRNAs 

      Sangiao-Alvarellos, Susana; Theofilatos, Konstantinos; Barwari, Temo; Gutmann, Clemens; Takov, Kaloyan; Singh, Bhawana; Juiz-Valiña, Paula; Varela-Rodríguez, Bárbara María; Outeiriño-Blanco, Elena; Duregotti, Elisa; Zampetaki, Anna; Lunger, Lukas; Ebenbichler, Christoph; Tilg, Herbert; García-Brao, María Jesús; Willeit, Peter; Mena, Enrique; Kiechl, Stefan; Cordido, Fernando; Mayr, Manuel (BMJ Publishing Group, 2020-10-01)
      [Abstract] INTRODUCTION: Bariatric surgery offers the most effective treatment for obesity, ameliorating or even reverting associated metabolic disorders, such as type 2 diabetes. We sought to determine the effects of ...

    • MicroARN circulantes en sangre de pacientes con cáncer de próstata 

      Medina Villaamil, Vanessa; Martínez-Breijo, S.; Portela-Pereira, P.; Quindós-Varela, María; Santamarina, Isabel; Antón-Aparicio, Luis M.; Gómez Veiga, Francisco (Elsevier, 2014)
      [Resumen] Introducción. Los microARN (miARN) son ARN reguladores de pequeño tamaño que no codifican para proteínas. La detección de células tumorales circulantes (CTC) proporcionaría información diagnóstica y pronóstica ...

    • MiR-19 family impairs adipogenesis by the downregulation of the PPARγ transcriptional network 

      Juiz-Valiña, Paula; Varela-Rodríguez, Bárbara María; Outeiriño-Blanco, Elena; García-Brao, María Jesús; Mena, Enrique; Cordido, Fernando; Sangiao-Alvarellos, Susana (MDPI, 2022-12-13)
      [Abstract] microRNAs (miRNAs) are a class of small endogenous RNA that play pivotal roles in both the differentiation and function of adipocytes during the development of obesity. Despite this, only a few miRNA families ...

    • Mortality in acromegaly diagnosed in older individuals in Spain is higher in women compared to the general spanish population 

      Biagetti, Betina; Iglesias, Pedro; Villar-Taibo, Rocío; Moure, María-Dolores; Paja, Miguel; Araújo-Castro, Marta; Ares, Jessica; Álvarez-Escola, Cristina; Vicente, Almudena; Álvarez Guivernau, Èlia; Novoa-Testa, Iria; Guerrero Pérez, Fernando; Cámara, Rosa; Lecumberri, Beatriz; García Gómez, Carlos; Bernebéu, Ignacio; Manjón, Laura; Gaztambide, Sonia; Cordido, Fernando; Webb, Susan M.; Menéndez-Torre, Edelmiro Luis; Díez, Juan J.; Simó, Rafael; Puig-Domingo, Manel (Oxford Academic, 2023-03-14)
      [Abstract] Context: There are no data on mortality of acromegaly diagnosed in older individuals. Objective: This work aimed to compare clinical characteristics, growth hormone-related comorbidities, therapeutic approaches, ...

    • Multiple biomarker tissue arrays: a computational approach to identifying protein-protein interactions in the EGFR/ERK signalling pathway 

      Medina Villaamil, Vanessa; Aparicio Gallego, Guadalupe; Valladares-Ayerbes, Manuel; Santamarina, Isabel; Antón-Aparicio, Luis M. (BioMed Central, 2012-09-01)
      [Abstract] Background. Many studies have demonstrated genetic and environmental factors that lead to renal cell carcinoma (RCC) and that occur during a protracted period of tumourigenesis. It appears suitable to identify ...

    • Non-functioning pituitary adenoma underwent surgery: a multicenter retrospective study over the last four decades (1977–2015) 

      Iglesias, Pedro; Arcano, Karina; Triviño, Vanessa; García-Sancho, Paula; Díez, Juan José; Cordido, Fernando; Villabona, Carles (Elsevier, 2017-04-04)
      [Abstract] Objective. To assess clinical features, diagnostic procedures, therapies and outcomes in patients with clinically non-functioning pituitary adenomas (NFPAs) surgically treated over the last four decades. Design ...

    • Novel potential predictive markers of sunitinib outcomes in long-term responders versus primary refractory patients with metastatic clear-cell renal cell carcinoma 

      Puente, Javier; Lainez, Nuria; Dueñas, Marta; Méndez-Vidal, María José; Esteban, Emilio; Castellano, Daniel; Martínez-Fernández, Mónica; Basterretxea, Laura; Juan-Fita, María José; Antón-Aparicio, Luis M.; León, Luis; Lambea, Julio; Pérez-Valderrama, Begoña; Vázquez, Sergio; Suárez, Cristina; García del Muro, Xavier; Gallardo, Enrique; Maroto, José Pablo; Samaniego, M. Luz; Suárez-Paniagua, Beatriz; Sanz, Julián; Paramio, Jesús M. (Impact Journals, 2017-03-23)
      [Abstract] Background: Several potential predictive markers of efficacy of targeted agents in patients with metastatic renal cell carcinoma (mRCC) have been identified. Interindividual heterogeneity warrants further ...

    • Obesity, adipose tissue, inflammation and update on obesity management 

      Cordido, Fernando; García-Mayor, Ricardo V.; Larranaga, Alejandra (Symbiosis, 2014-11-12)
      [Abstract] Obesity is a serious, common and growing problem. Obesity can be defined as an excess of body fat. Its clinical management is complex and frequently unsuccessful. It has only recently been regarded as a chronic ...

    • Oral glucose-stimulated growth hormone (GH) test in adult GH deficiency patients and controls: potential utility of a novel test 

      Pena-Bello, Lara; Seoane-Pillado, Teresa; Sangiao-Alvarellos, Susana; Outeiriño-Blanco, Elena; Varela-Rodríguez, Bárbara María; Juiz-Valiña, Paula; Cordido, María; Cordido, Fernando (Elsevier para European Federation of Internal Medicine, 2017-06-09)
      [Abstract] Context. The diagnosis of adult GH deficiency requires confirmation with a GH stimulation test. Oral glucose (OG) administration affects GH secretion, initially decreasing and subsequently stimulating GH ...

    • Patología tiroidea en atención primaria 

      Núñez Vázquez, Ángel; Cordido, Fernando; Gómez Gómez, Natalia; Lois Rodríguez, Marta; Cordido, María; Louro González, Arturo (Elsevier, 2016-12)