Listar Grupo Fisiopatoloxía Endócrina, Nutricional e Médica (FENM) por título

Mostrando ítems 110-121 de 121

    • Testicular expression of the Lin28/let-7 system: hormonal regulation and changes during postnatal maturation and after manipulations of puberty 

      Sangiao-Alvarellos, Susana; Manfredi-Lozano, María; Ruiz-Pino, Francisco; León, Silvia; Morales, Concepción; Cordido, Fernando; Gaytán, Francisco; Pinilla, Leonor; Tena-Sempere, Manuel (Nature, 2015-10-23)
      [Abstract] The Lin28/let-7 system, which includes the RNA-binding proteins, Lin28a/Lin28b, and let-7 miRNAs, has emerged as putative regulator of puberty and male gametogenesis; yet, its expression pattern and regulation ...

    • The decreased growth hormone response to growth hormone releasing hormone in obesity is associated to cardiometabolic risk factors 

      Cordido, Fernando; García-Buela, Jesús; Sangiao-Alvarellos, Susana; Martínez, Teresa; Vidal, Ovidio (Hindawi, 2010)
      [Abstract] The aim of the present study was to evaluate the relationship between GHRH-induced GH secretion in obese premenopausal women and cardiovascular risk markers or insulin resistance. Premenopausal obese women, aged ...

    • The Lin28/Let-7 system in early human embryonic tissue and ectopic pregnancy 

      Lozoya, Teresa; Domínguez, Francisco; Romero-Ruiz, Antonio; Steffani, Liliana; Martínez, Sebastián; Monterde, Mercedes; Ferri, Blanca; Núñez, María José; Romero-Espinós, Ainhoa; Zamora, Omar; Guerra, Marta; Sangiao-Alvarellos, Susana; Vega, Olivia; Simón, Carlos; Pellicer, Antonio; Tena-Sempere, Manuel (PLoS One, 2014-01-31)
      [Abstract] Our objective was to determine the expression of the elements of the Lin28/Let-7 system, and related microRNAs (miRNAs), in early stages of human placentation and ectopic pregnancy, as a means to assess the ...

    • The modality of dialysis does not influence atheromatous vascular disease progression or cardiovascular outcomes in dialysis patients without previous cardiovascular disease 

      Borrás Sans, Mercé; Pérez-Fontán, Miguel; Martínez-Alonso, Monserrat; Bajo, Auxiliadora; Betriu, Angels; Valdivielso, José Manuel; Fernández, Elvira (PLOS, 2017-11-02)
      [Abstract] Background. There is limited and inconclusive information regarding the influence of the modality of renal replacement therapy on the atherosclerotic burden of patients on dialysis. The aim of this study was to ...

    • Thyroid function alteration in obesity and the effect of bariatric surgery 

      Cordido, María; Juiz-Valiña, Paula; Urones Cuesta, Paula; Sangiao-Alvarellos, Susana; Cordido, Fernando (MDPI, 2022-02-28)
      [Abstract] The most common endocrine disease in obesity is hypothyroidism and secondary endocrine alterations, including abnormal thyroid function, are frequent in obesity. It is unclear whether impaired thyroid function ...

    • Tissue effects of glutamine in rectal cancer patients treated with preoperative chemoradiotherapy 

      Vidal-Casariego, Alfonso; Hernando-Martín, Mercedes; Calleja-Fernández, Alicia; Cano-Rodríguez, Isidoro; Cordido, Fernando; Ballesteros-Pomar, María D. (SENPE (Sociedad Española de Nutrición Parentelar y Entelar), 2015)
      [Abstract] Background: The aim was to evaluate the effects of glutamine on tumor regression and histological damage in patients with rectal patients following chemoradiotherapy previous to surgery. Material and methods: ...

    • Tratamiento quirúrgico de la obesidad: recomendaciones prácticas basadas en la evidencia 

      Morales, M. José; Díaz-Fernández, María Jesús; Caixás, Assumpta; Goday, Albert; Moreiro, José; Arrizabalaga, Juan José; Calañas-Continente, Alfonso; Cuatrecasas, Guillem; García Luna, Pedro Pablo; Masmiquel, Lluís; Monereo, Susana; Moreno, Basilio; Ricart, Wilfred; Vidal, Josep; Cordido, Fernando (Elsevier, 2008)
      [Resumen] La obesidad mórbida es, habitualmente, refractaria a los tratamientos convencionales, por lo que la modificación de hábitos dietéticos y de actividad física y/o el uso de fármacos consiguen pérdidas de peso ...

    • Treatment of sunitinib-induced hypertension in solid tumor by nitric oxide donors 

      León-Mateos, L.; Mosquera, J.; Antón-Aparicio, Luis M. (Elsevier, 2015-09-10)
      [Abstract] Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) are overexpressed in the majority of renal cell carcinomas. This characteristic has supported the rationale of targeting VEGF-driven tumour ...

    • Treatment with growth hormone for adults with growth hormone deficiency syndrome: benefits and risks 

      Díez, Juan José; Sangiao-Alvarellos, Susana; Cordido, Fernando (MDPI, 2018-03-17)
      [Abstract] Pharmacological treatment of growth hormone deficiency (GHD) in adults began in clinical practice more than 20 years ago. Since then, a great volume of experience has been accumulated on its effects on the ...

    • Tyrosine kinase inhibitors reprogramming immunity in renal cell carcinoma: rethinking cancer immunotherapy 

      Antón-Aparicio, Luis M.; Peláez Fernández, Ignacio; Cassinello Espinosa, J. (Springer, 2017-04-13)
      [Abstract] The immune system regulates angiogenesis in cancer by way of both pro- and antiangiogenic activities. A bidirectional link between angiogenesis and the immune system has been clearly demonstrated. Most antiangiogenic ...

    • Use of lanreotide in combination with cabergoline or pegvisomant in patients with acromegaly in the clinical practice: the ACROCOMB study 

      Puig-Domingo, Manuel; Soto, Alfonso; Venegas, Eva; Vílchez, Ricardo; Blanco, Concepción; Cordido, Fernando; Lucas, Tomás; Marazuela, Mónica; Casany, Rosa; Cuatrecasas, Guillem; Fajardo, Carmen; Gálvez, María Ángeles; Maraver, Silvia; Martín, Tomás; Romero, Enrique; Paja, Miguel; Picó, Antonio; Bernabéu, Ignacio; Resmini, Eugenia (Elsevier, 2016-11-04)
      [Abstract] PURPOSE: To describe real-world use of lanreotide combination therapy for acromegaly. PATIENTS AND METHODS: ACROCOMB is a retrospective observational Spanish study of patients with active acromegaly treated ...

    • Vaspin and amylin are expressed in human and rat placenta and regulated by nutritional status 

      Caminos, Jorge Eduardo; Bravo, Susana Belén; Garcés, María Fernanda; González, Carmen Ruth; Cepeda, Libia Alexandra; González, Adriana C.; Nogueiras, Rubén; Gallego, Rosalía; García-Caballero, Tomás; Cordido, Fernando; López, Miguel; Diéguez, Carlos (Universidad de Murcia, 2009)
      [Abstract] Amylin (islet amyloid polypeptide) and vaspin (visceral adipose tissue specific serpin) are gut and adipocyte hormones involved in the regulation of body weight homeostasis. The aim of this study was to examine ...