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Feedback control of stochastic gene switches using PIDE models
(Elsevier, 2022)
[Abstract]: Achieving control of gene regulatory circuits is one of the goals of synthetic biology, as a way to regulate cellular functions for useful purposes (in biomedical, environmental or industrial applications). The ...
First passage times as a measure of hysteresis in stochastic gene regulatory circuits
(Elsevier, 2022)
[Abstract]: In the context of phenotype switching and cell fate determination, numerousexperimental studies report hysteresis, despite the fact that the (forward) Chemical Master Equation governing the inherently stochastic ...