• Feedback control of stochastic gene switches using PIDE models 

  Fernández, Christian; Faquir, Hamza; Pájaro Diéguez, Manuel; Otero-Muras, Irene (Elsevier, 2022)

  [Abstract]: Achieving control of gene regulatory circuits is one of the goals of synthetic biology, as a way to regulate cellular functions for useful purposes (in biomedical, environmental or industrial applications). The ...

• The Impact of Edge Displacement Vaserstein Distance on UD Parsing Performance 

  Anderson, Mark; Gómez-Rodriguez, Carlos (The MIT Press, 2022)

  [Abstract] We contribute to the discussion on parsing performance in NLP by introducing a measurement that evaluates the differences between the distributions of edge displacement (the directed distance of edges) seen in ...

• How Agent-based modeling can help to foster sustainability projects 

  Sánchez-Maroño, Noelia; Rodriguez Arias, Alejandro; Dumitru, Adina; Lema-Blanco, Isabel; Guijarro-Berdiñas, Bertha; Alonso-Betanzos, Amparo (Elsevier, 2022)

  [Abstract] The Sustainable Development Goals (SDGs) adopted by the United Nations require relevant social changes that sometimes involve the development of innovative projects that cause rejection and confrontation. ...

• Extracellular Vesicles Enriched in Connexin 43 Promote a Senescent Phenotype in Bone and Synovial Cells Contributing to Osteoarthritis Progression 

  Varela-Eirín, Marta; Carpintero-Fernández, Paula; Guitián-Caamaño, Amanda; Varela Vázquez, Adrián; García-Yuste, Alejandro; Sánchez Temprano, Agustín; Bravo López, Susana Belén; Yáñez-Cabanas, José; Fonseca, Eduardo; Largo, R.; Mobasheri, Ali; Caeiro, José Ramón; Mayán, María D. (Springer Nature, 2022)

  [Abstract] The accumulation of senescent cells is a key characteristic of aging, leading to the progression of age-related diseases such as osteoarthritis (OA). Previous data from our laboratory has demonstrated that high ...

• The Red Cage: Implementation of pH-Responsiveness Within a Macrobicyclic Pyridinium-Based Molecular Host 

  Cortón, Pablo; Wang, Hongye; Neira, Iago; Blanco-Gómez, Arturo; Pazos, Elena; Peinador, Carlos; Li, Hao; García, Marcos D. (Royal Society of Chemistry, 2021-11-09)

  [Abstract] We present herein the implementation of pH-responsiveness into a new polycationic macrobicyclic structure, namely what we have termed the “red cage”. The hydrolytically-stable cryptand-like compound has been ...

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