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Performance of gene-expression profiling test score variability to predict future clinical events in heart transplant recipients
(BioMed Central, 2015-10-09)
[Abstract]
Background. A single non-invasive gene expression profiling (GEP) test (AlloMap®) is often used to discriminate if a heart transplant recipient is at a low risk of acute cellular rejection at time of testing. ...
Clinical usefulness of gene-expression profile to rule out acute rejection after heart transplantation: CARGO II
(Oxford University Press en nombre de European Society of Cardiology, 2016-01-07)
[Abstract] Aims. A non-invasive gene-expression profiling (GEP) test for rejection surveillance of heart transplant recipients originated in the USA. A European-based study, Cardiac Allograft Rejection Gene Expression ...
An integrated molecular diagnostic report for heart transplant biopsies using an ensemble of diagnostic algorithms
(Elsevier, 2019-02-06)
[Abstract] BACKGROUND. We previously reported a microarray-based diagnostic system for heart transplant endomyocardial biopsies (EMBs), using either 3-archetype (3AA) or 4-archetype (4AA) unsupervised algorithms to estimate ...
Molecular states associated with dysfunction and graft loss in heart transplants
(Elsevier, 2023-11-30)
[Abstract]
Background: We explored the changes in gene expression correlating with dysfunction and graft failure in endomyocardial biopsies.
Methods: Genome-wide microarrays (19,462 genes) were used to define mRNA ...