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Frailty syndrome and genomic instability in older adults: suitability of the cytome micronucleus assay as a diagnostic tool
[Abstract] Frailty, a condition involving increased risk of disability and mortality in older adults, has emerged as a reliable way to predict the effect of aging. Genomic instability may help to anticipate recognition of ...
Frailty in older adults Is associated with plasma concentrations of inflammatory mediators but not with lymphocyte subpopulations
[Abstract] Frailty denotes a multidimensional syndrome that gives rise to vulnerability to stressors and leads to an increase of the age-related decline of different physiological systems and cognitive abilities. Aging-related ...
Exploring genetic outcomes as frailty biomakers
[Abstract] Frailty has emerged as a reliable measure of the aging process. Because the early detection of frailty is crucial to prevent or even revert it, the use of biomarkers would allow an earlier and more objective ...
Reference ranges of lymphocyte subsets in non-frail older adults
Serum cortisol but not oxidative stress biomarkers are related to frailty: results of a cross-sectional study in Spanish older adults
[Abstract] Frailty is a multidimensional geriatric syndrome of loss of reserves and increased vulnerability to negative health outcomes. Cortisol, the major hormone of the hypothalamic pituitary adrenal (HPA) axis, and ...