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Analysis of variants in the HCN4 gene and in three single nucleotide polymorphisms of the CYP3A4 gene for association with ivabradine reduction in heart rate: a preliminary report
(Via Médica, 2016)
[Abstract] Background: Ivabradine, a selective bradycardic drug, inhibits the If. In patients with heart failure (HF), ivabradine reduces the risk of rehospitalization and mortality. The average heart rate (HR) reduction ...
Circulating Galectin-3 Following Heart Transplant: Long-term Dynamics and Prognostic Value
(Elsevier, 2018-11-23)
[Abstract] Introduction and objectives: Circulating galectin-3 (Gal-3) is elevated and significantly correlates with all-cause and cardiovascular mortality in patients with heart failure. However, the relationship between ...
Clinical Profile and Causes of Death According to Ejection Fraction in Patients With Heart Failure Cared for in a Specialized Cardiology Unit
(Elsevier, 2021-05-14)
[Abstract]
Background and objective.
Patients with heart failure are classified into three phenotypes based on left ventricular ejection fraction. This work aimed to compare the clinical profile, treatment, prognosis, ...
Real World Comparison of Spironolactone and Eplerenone in Patients With Heart Failure
(Elsevier, 2022-01-06)
[Abstract] Aims. In the absence of previous direct comparative studies, we aimed to evaluate the effectiveness of spironolactone and eplerenone in patients with heart failure and reduced ejection fraction (HFrEF) in a ...
Comparison of predicted and observed mortality in patients with heart failure treated at a specialized unit
(Elsevier, 2020-01-21)
[Abstract] Introduction and objectives: To analyze survival in heart failure (HF) patients treated at a specialized unit.
Methods: Prospective cohort-based study of HF patients treated at a specialized unit from 2011 ...
Usefulness of the INTERMACS scale for predicting outcomes after urgent heart transplantation
(Elsevier, 2011)
[Abstract] Introduction and objectives. Our aim was to assess the prognostic value of the INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) scale in patients undergoing urgent heart transplantation ...
Chronic anemia in heart transplant patients: prevalence, risk factors, and prognostic significance
(Elsevier, 2007)
[Abstract] Introduction and objectives. Data on chronic anemia following heart transplantation (HT) are scarce and contradictory. Our aims were to determine the prevalence of chronic anemia after HT, to identify predisposing ...
Quinolone-related Achilles tendinopathy in heart transplant patients: incidence and risk factors
(Elsevier, 2008-01-08)
[Abstract] Background. A high incidence of Achilles tendinopathy—tendinitis or rupture—has been observed after quinolone treatment in lung and kidney transplant patients. In the absence of relevant published data, we aimed ...
Polymorphisms in genes related to the complement system and antibody-mediated cardiac allograft rejection
(Elsevier, 2017-07-15)
[Abstract] Background. Heart transplantation (HT) is a life-saving treatment for patients with end-stage heart failure. One of the main problems after HT is the humoral response termed antibody-mediated rejection (AMR). ...
AGT haplotype in ITGA4 gene is related to antibody-mediated rejection in heart transplant patients
(Stanislaw Stepkowski,, 2019-07-23)
[Abstract] Introduction.
One of the main problems involved in heart transplantation (HT) is antibody-mediated rejection
(AMR). Many aspects of AMR are still unresolved, including its etiology, diagnosis and
treatment. ...