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A single nucleotide polymorphism in the Il17ra promoter is associated with functional severity of ankylosing spondylitis
(PLoS, 2016-07-14)
[Abstract] The aim of this study was to identify new genetic variants associated with the severity of ankylosing spondylitis (AS). We sequenced the exome of eight patients diagnosed with AS, selected on the basis of the ...
Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1
(Nature, 2015-05-21)
[Abstract] Article
Open Access
Published: 21 May 2015
Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1
Adrian Cortes, Sara L. Pulit, Paul J. ...
Lack of replication of interactions between polymorphisms in rheumatoid arthritis susceptibility: case–control study
(BioMed Central, 2014-09-27)
[Abstract] INTRODUCTION:
Approximately 100 loci have been definitively associated with rheumatoid arthritis (RA) susceptibility. However, they explain only a fraction of RA heritability. Interactions between polymorphisms ...