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Severe Neurometabolic Phenotype in NPC1−/− Zebrafish With a C-Terminal Mutation
(Frontiers, 2023-03-17)
[Abstract] Niemann Pick disease type C (NPC) is an autosomal recessive neurodegenerative lysosomal disorder characterized by an accumulation of lipids in different organs. Clinical manifestations can start at any age and ...
Zebrafish Models for the Safety and Therapeutic Testing of Nanoparticles with a Focus on Macrophages
(MDPI, 2021-07-09)
[Abstract] New nanoparticles and biomaterials are increasingly being used in biomedical research for drug delivery, diagnostic applications, or vaccines, and they are also present in numerous commercial products, in the ...