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Analysis of variants in the HCN4 gene and in three single nucleotide polymorphisms of the CYP3A4 gene for association with ivabradine reduction in heart rate: a preliminary report
(Via Médica, 2016)
[Abstract] Background: Ivabradine, a selective bradycardic drug, inhibits the If. In patients with heart failure (HF), ivabradine reduces the risk of rehospitalization and mortality. The average heart rate (HR) reduction ...
Circulating Galectin-3 Following Heart Transplant: Long-term Dynamics and Prognostic Value
(Elsevier, 2018-11-23)
[Abstract] Introduction and objectives: Circulating galectin-3 (Gal-3) is elevated and significantly correlates with all-cause and cardiovascular mortality in patients with heart failure. However, the relationship between ...
Usefulness of the INTERMACS scale for predicting outcomes after urgent heart transplantation
(Elsevier, 2011)
[Abstract] Introduction and objectives. Our aim was to assess the prognostic value of the INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) scale in patients undergoing urgent heart transplantation ...
Polymorphisms in genes related to the complement system and antibody-mediated cardiac allograft rejection
(Elsevier, 2017-07-15)
[Abstract] Background. Heart transplantation (HT) is a life-saving treatment for patients with end-stage heart failure. One of the main problems after HT is the humoral response termed antibody-mediated rejection (AMR). ...
AGT haplotype in ITGA4 gene is related to antibody-mediated rejection in heart transplant patients
(Stanislaw Stepkowski,, 2019-07-23)
[Abstract] Introduction.
One of the main problems involved in heart transplantation (HT) is antibody-mediated rejection
(AMR). Many aspects of AMR are still unresolved, including its etiology, diagnosis and
treatment. ...
Indoleamine, 2-3 dioxygenase activity could be an early marker of graft rejection in heart transplantation
(Elsevier, 2012-11-10)
[Abstract] Background. The indoleamine, 2-3 dioxygenase (IDO) is an inducible intracellular enzyme with immunosuppressive effects mainly on lymphocyte populations. It has been postulated that indirect determination of IDO ...