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Analysis of variants in the HCN4 gene and in three single nucleotide polymorphisms of the CYP3A4 gene for association with ivabradine reduction in heart rate: a preliminary report
(Via Médica, 2016)
[Abstract] Background: Ivabradine, a selective bradycardic drug, inhibits the If. In patients with heart failure (HF), ivabradine reduces the risk of rehospitalization and mortality. The average heart rate (HR) reduction ...
Prognostic significance of heart rate and its long-term trend in cardiac transplant patients
(Elsevier para Sociedad Española de Cardiología, 2015-04-11)
[Abstract] Introduction and objectives. The aim of the present study was to examine the prognostic significance of heart rate and its trend in heart transplantation.
Methods. This observational study enrolled 170 patients ...
Venous thromboembolism in heart transplant recipients: Incidence, recurrence and predisposing factors
(Elsevier para International Society for Heart and Lung Transplantation, 2015-10-02)
[Abstract] Background. A high frequency of venous thromboembolism (VTE) has been observed after lung, kidney, and liver transplantation. However, data about the incidence of this complication among heart transplant (HT) ...
Clinical evaluation of rosuvastatin in heart transplant patients with hypercholesterolemia and therapeutic failure of other statin regimens: short-term and long-term efficacy and safety results
(Wiley, 2015-04-23)
[Abstract] We conducted an observational study of 30 heart transplant recipients with serum low-density lipoprotein cholesterol (LDL-c) >100 mg/dl despite previous statin therapy, who were treated with rosuvastatin 10 mg ...
Usefulness of the INTERMACS scale for predicting outcomes after urgent heart transplantation
(Elsevier, 2011)
[Abstract] Introduction and objectives. Our aim was to assess the prognostic value of the INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) scale in patients undergoing urgent heart transplantation ...
Polymorphisms in genes related to the complement system and antibody-mediated cardiac allograft rejection
(Elsevier, 2017-07-15)
[Abstract] Background. Heart transplantation (HT) is a life-saving treatment for patients with end-stage heart failure. One of the main problems after HT is the humoral response termed antibody-mediated rejection (AMR). ...
Indoleamine, 2-3 dioxygenase activity could be an early marker of graft rejection in heart transplantation
(Elsevier, 2012-11-10)
[Abstract] Background. The indoleamine, 2-3 dioxygenase (IDO) is an inducible intracellular enzyme with immunosuppressive effects mainly on lymphocyte populations. It has been postulated that indirect determination of IDO ...
Incidence, Risk Factors and Prognostic Impact of Cytomegalovirus Infection After Heart Transplantation
(Elsevier, 2020-03-20)
[Abstract] Introduction and objectives. To assess the risk factors of CMV infection after heart transplant (HT) and its influence on long-term prognosis.
Methods. We conducted a retrospective single-centre study of ...