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Mitochondrial haplogroups H and J: risk and protective factors for ischemic cardiomyopathy
(PLoS, 2012-08-28)
[Abstract] Background. Since mitochondria are the principal source of reactive oxygen species (ROS), these organelles may play an important role in ischemic cardiomyopathy (IC) development. The mitochondrial genome may ...
Indoleamine, 2-3 dioxygenase activity could be an early marker of graft rejection in heart transplantation
(Elsevier, 2012-11-10)
[Abstract] Background. The indoleamine, 2-3 dioxygenase (IDO) is an inducible intracellular enzyme with immunosuppressive effects mainly on lymphocyte populations. It has been postulated that indirect determination of IDO ...