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Mitochondrial DNA (mtDNA) haplogroups J and H are differentially associated with the methylation status of articular cartilage: potential role in apoptosis and metabolic and developmental processes
(Wiley, 2019-02-12)
[Abstract] Objective. To analyze the influence of mitochondrial genome variation on the DNA methylome of articular cartilage.
Methods. DNA methylation profiling was performed using data deposited in the NCBI Gene ...
Specific premature epigenetic aging of cartilage in osteoarthritis
(Impact Journals, 2016-09-28)
[Abstract] Osteoarthritis (OA) is a disease affecting multiple tissues of the joints in the elderly, but most notably articular cartilage. Premature biological aging has been described in this tissue and in blood cells, ...