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Performance of gene-expression profiling test score variability to predict future clinical events in heart transplant recipients
(BioMed Central, 2015-10-09)
[Abstract]
Background. A single non-invasive gene expression profiling (GEP) test (AlloMap®) is often used to discriminate if a heart transplant recipient is at a low risk of acute cellular rejection at time of testing. ...
Clinical usefulness of gene-expression profile to rule out acute rejection after heart transplantation: CARGO II
(Oxford University Press en nombre de European Society of Cardiology, 2016-01-07)
[Abstract] Aims. A non-invasive gene-expression profiling (GEP) test for rejection surveillance of heart transplant recipients originated in the USA. A European-based study, Cardiac Allograft Rejection Gene Expression ...
Validation of a clinical-grade assay to measure donor-derived cell-free DNA in solid organ transplant recipients
(Elsevier para American Society for Investigative Pathology and the Association for Molecular Pathology, 2016-10-07)
[Abstract] The use of circulating cell-free DNA (cfDNA) as a biomarker in transplant recipients offers advantages over invasive tissue biopsy as a quantitative measure for detection of transplant rejection and immunosuppression ...