Listar 1. Investigación por autor "Sobrino, Tomás"

Mostrando ítems 1-6 de 6

    • A multitrait genetic study of hemostatic factors and hemorrhagic transformation after stroke treatment 

      Gallego-Fábrega, Cristina; Temprano-Sagrera, Gerard; Cárcel-Márquez, Jara; Muiño, Elena; Cullel, Natalia; Lledós, Miquel; Llucià-Carol, Laia; Martín-Campos, Jesús M.; Sobrino, Tomás; Castillo, José; Millán, Mónica; Muñoz-Narbona, Lucía; López-Cancio Martínez, Elena; Ribó, Marc; Álvarez-Sabín, José; Jiménez-Conde, Jordi; Roquer, Jaume; Tur, Silvia; Obach, Victor; Arenillas, Juan; Segura, Tomás; Serrano-Heras, Gemma; Martí-Fàbregas, Joan; Freijo Guerrero, María del Mar; Moniche Álvarez, Francisco; Castellanos, María del Mar; Morrison, Alana C.; Smith, Nicholas L.; de Vries, Paul S.; Fernández-Cadenas, Israel; Sabater-Lleal, María (Elsevier, 2023-12-15)
      [Abstract] Background: Thrombolytic recombinant tissue plasminogen activator (r-tPA) treatment is the only pharmacologic intervention available in the ischemic stroke acute phase. This treatment is associated with an ...

    • Association of high serum levels of growth factors with good outcome in ischemic stroke: a multicenter study 

      Sobrino, Tomás; Rodríguez-Yáñez, Manuel; Campos, Francisco; Iglesias-Rey, Ramón; Millán, Mónica; Pérez de la Osa, Natalia; Dávalos, Antonio; Delgado-Mederos, Raquel; Martínez-Domeño, Alejandro; Martí-Fábregas, Joan; Castellanos, María del Mar; Serena, Joaquín; Lago, Aida; Díez-Tejedor, Exuperio; Castillo, José (Springer Nature, 2019-11-25)
      [Abstract] The main objective of this research work was to study the association of serum levels of growth factors (GF) and SDF-1α with the functional outcome and reduction of lesion volume in ischemic stroke patients. In ...

    • Random Forest-Based Prediction of Stroke Outcome 

      Fernández-Lozano, Carlos; Hervella, Pablo; Mato-Abad, Virginia; Rodríguez-Yáñez, Manuel; Suárez-Garaboa, Sonia; López Dequidt, Iria Alejandra; Estany-Gestal, Ana; Sobrino, Tomás; Campos, Francisco; Castillo, José; Rodríguez-Yáñez, Santiago; Iglesias Rey, Ramón (Nature Research, 2021)
      [Abstract] We research into the clinical, biochemical and neuroimaging factors associated with the outcome of stroke patients to generate a predictive model using machine learning techniques for prediction of mortality and ...

    • RP11-362K2.2:RP11-767I20.1 genetic variation is associated with post-reperfusion therapy parenchymal hematoma: a GWAS meta-analysis 

      Muiño, Elena; Cárcel-Márquez, Jara; Carrera, Caty; Llucià-Carol, Laia; Gallego-Fábrega, Cristina; Cullel, Natalia; Lledós, Miquel; Castillo, José; Sobrino, Tomás; Campos, Francisco; Rodríguez-Castro, Emilio; Millán, Mónica; Muñoz-Narbona, Lucía; Bustamante, Alejandro; López-Cancio Martínez, Elena; Ribó, Marc; Álvarez-Sabín, José; Jiménez-Conde, Jordi; Roquer, Jaume; Giralt-Steinhauer, Eva; Soriano-Tárraga, Carolina; Vives-Bauza, Cristófol; Díaz Navarro, Rosa; Tur, Silvia; Obach, Victor; Arenillas, Juan; Segura, Tomás; Serrano-Heras, Gemma; Martí-Fàbregas, Joan; Delgado-Mederos, Raquel; Camps-Renom, Pol; Prats-Sánchez, Luis; Guisado, Daniel; Guasch, Marina; Marin, Rebeca; Martínez-Domeño, Alejandro; Freijo Guerrero, María del Mar; Moniche Álvarez, Francisco; Cabezas, Juan Antonio; Castellanos, María del Mar; Krupinsky, Jerzy; Strbian, Daniel; Tatlisumak, Turgut; Thijs, Vincent; Lemmens, Robin; Slowik, Agnieszka; Pera, Joanna; Heitsch, Laura; Ibáñez, Laura; Cruchaga, Carlos; Dhar, Rajat; Lee, Jin-Moo; Montaner, Joan; Fernández-Cadenas, Israel (MDPI, 2021-07-16)
      [Abstract] Stroke is one of the most common causes of death and disability. Reperfusion therapies are the only treatment available during the acute phase of stroke. Due to recent clinical trials, these therapies may increase ...

    • Utilidad del OCT preclínico para la caracterización retiniana de la enfermedad de Alzheimer con un modelo animal genéticamente modificado 

      Gil-Martínez, María; Cuartero-Martínez, A.; Custodia, A.; Gómez-Lado, Noemí; Ouro, Alberto; Moura, Joaquim de; Novo Buján, Jorge; Ortega Hortas, Marcos; Aguiar, Pablo; Sobrino, Tomás; Fernández Ferreiro, Anxo (Sociedad Española de Retina y Vítreo, 2023)
      [Resumen]: La enfermedad de Alzheimer (EA) es una enfermedad neurodegenerativa caracterizada por la acumulación de placas de ß-amiloide (ßA) y proteína TAU que se depositan en las placas seniles y causan efectos tóxicos ...

    • Worse outcome in stroke patients treated with rt-PA without early reperfusion: associated factors 

      Iglesias-Rey, Ramón; Rodríguez-Yáñez, Manuel; Rodríguez-Castro, Enrique; Pumar, José Manuel; Arias, Susana; Santamaría, María; López-Dequidt, Iria; Hervella, Pablo; Correa-Paz, Clara; Sobrino, Tomás; Vivien, Denis; Campos, Francisco; Castellanos, María del Mar; Castillo, José (Springer Nature, 2017-11-07)
      [Abstract] Based on preclinical studies suggesting that recombinant tissue plasminogen activator (rt-PA) may promote ischemic brain injuries, we investigated in patients the possible risk of worse clinical outcome after ...