Listar 1. Investigación por autor "González de Aledo, Manuel"
Mostrando ítems 1-2 de 2
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CRISPR-Cas, a Revolution in the Treatment and Study of ESKAPE Infections: Pre-Clinical Studies
González de Aledo, Manuel; González-Bardanca, Mónica; Blasco, Lucía; Pacios Santamaría, Olga; Bleriot Rial, Ines; Fernández-García, Laura; Fernández-Quejo, Melisa; López, María; Bou, Germán; Tomás, María (MDPI, 2021-06-22)[Abstract] One of the biggest threats we face globally is the emergence of antimicrobial-resistant (AMR) bacteria, which runs in parallel with the lack in the development of new antimicrobials. Among these AMR bacteria ... -
Genomic Analysis of Molecular Bacterial Mechanisms of Resistance to Phage Infection
Ambroa, Antón; Blasco, Lucía; López, María; Pacios Santamaría, Olga; Bleriot Rial, Ines; Fernández-García, Laura; González de Aledo, Manuel; Ortiz-Cartagena, Concha; Millard, Andrew; Tomás, María (Frontiers, 2022-02-17)[Abstract] To optimize phage therapy, we need to understand how bacteria evolve against phage attacks. One of the main problems of phage therapy is the appearance of bacterial resistance variants. The use of genomics to ...