Early-life Disease Environment and Adult Height in Historical Populations
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Early-life Disease Environment and Adult Height in Historical PopulationsData
2022Cita bibliográfica
Casal B, Rivera B, and Mourelle E. (2022) Early-life disease environment and adult height in historical populations. Journal of Developmental Origins of Health and Disease 13: 330–337. doi: 10.1017/S2040174421000337
Resumo
[Abstract] Nutrition and the incidence of diseases during early life are considered environmental factors that determine people’s height when they become adults. While there is extensive literature focusing on the relationship between physical growth, general mortality and infant mortality rates, few studies analyse the impact of certain disease groups on the final height of historical populations. Using regional mortality rates by causes of death, the main objective of this study is to determine the onset of the disease environment during early life for populations born in Spain between 1916 and 1930, and its relationship with the stature reached at 21 years of age. A population-averaged model is performed on epidemic-infectious, gastrointestinal, and congenital diseases during the gestation period and first year of life. The disease burden in early life had a statistically significant negative effect on adult stature. These results support the premise that an improvement in the disease environment could lead to a greater number of short children surviving and therefore a decrease in the average height.
Palabras chave
Disease burden
Epidemiological transition
Height
Historical populations
Epidemiological transition
Height
Historical populations
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Dereitos
© The Author(s)
ISSN
2040-1744
2040-1752
2040-1752