Listar GI-REACT! - Artigos por autor "Tei, Lorenzo"
Mostrando ítems 1-5 de 5
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Accelerating water exchange in GdIII–DO3A-derivatives by favouring the dissociative mechanism through hydrogen bonding
Leone, Loredana; Esteban-Gómez, David; Platas-Iglesias, Carlos; Milanesio, Marco; Tei, Lorenzo (Royal Society of Chemistry, 2018-12-10)[Abstract] The GdIII-complexes of DO3A-acetophenone and ortho- or para- hydroxyacetophenone ligands have been investigated to assess the effect of the presence of a phenol group on the relaxivity and on the water exchange ... -
Defining the Conditions for the Development of the Emerging Class of Feᴵᴵᴵ-Based MRI Contrast Agents
Baranyai, Zsolt; Carniato, Fabio; Nucera, Alessandro; Horváth, Dávid; Tei, Lorenzo; Platas-Iglesias, Carlos; Botta, Mauro (Royal Society of Chemistry, 2021-07-26)[Abstract] Fe(III) complexes are attracting growing interest in chemists developing diagnostic probes for Magnetic Resonance Imaging because they leverage on an endogenous metal and show superior stability. However, in ... -
Dimer formation of GdDO3A-arylsulfonamide complexes causes loss of pH-dependency of relaxivity
Wacker, Anja; Carniato, Fabio; Platas-Iglesias, Carlos; Esteban-Gómez, David; Wester, Hans-Jürgen; Tei, Lorenzo; Notni, Johannes (Royal Society of Chemistry, 2017-11-06)[Abstract] Gadolinium(III) complexes with pH-dependent relaxivities have been proposed as responsive magnetic resonance imaging (MRI) contrast agents (CA) for mapping of pH value in living subjects. The latter is clinically ... -
Optimising the relaxivities of Mn2+ complexes by targeting human serum albumin (HSA)
Forgács, Attila; Tei, Lorenzo; Baranyai, Zsolt; Esteban-Gómez, David; Platas-Iglesias, Carlos; Botta, Mauro (Royal Society of Chemistry, 2017-07-14)[Abstract] We report two novel macrocyclic ligands based on the 1,4-DO2AM platform (1,4-DO2AM = 2,2′-(1,4,7,10-tetraazacyclododecane-1,4-diyl)diacetamide) and containing two benzyl groups attached either to the nitrogen ... -
Surprising Complexity of the [Gd(AAZTA)(H2O)2]− Chelate Revealed by NMR in the Frequency and Time Domains
Lalli, Daniela; Carniato, Fabio; Tei, Lorenzo; Platas-Iglesias, Carlos; Botta, Mauro (American Chemical Society, 2021-12-10)[Abstract] Typically, Ln(III) complexes are isostructural along the series, which enables studying one particular metal chelate to derive the structural features of the others. This is not the case for [Ln(AAZTA)(H2O)x]− ...