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Okadaic Acid Induces Morphological Changes, Apoptosis and Cell Cycle Alterations in Different Human Cell Types
(Royal Society of Chemistry (Gran Bretaña), 2011-03-28)
[Abstract] Okadaic acid (OA) is a marine toxin produced by dinoflagellate species which is frequently accumulated in molluscs usual in the human diet. The exact action mechanism of OA has not been described yet and the ...
Induction of Oxidative DNA Damage by the Marine Toxin Okadaic Acid Depends on Human Cell Type
(Elsevier, 2011-03-01)
[Abstract] The marine toxin okadaic acid (OA) is the main representative of diarrhoeic shellfish poisoning (DSP) toxins. Its ingestion induces nausea, vomiting, diarrhoea and abdominal ache. It has also been found to trigger ...
Cytogenetic Effects Induced by Prestige Oil on Human Populations: The Role of Polymorphisms in Genes Involved in Metabolism and DNA Repair
(Elsevier, 2008-04-18)
[Abstract] The spill from the oil tanker Prestige (NW Spain, November 2002) was perhaps the biggest ecological disaster that happened worldwide in the last decades. As a consequence of this catastrophe a general concern ...
Assessment of Okadaic Acid Effects on Cytotoxicity, DNA Damage and DNA Repair in Human Cells
(Elsevier, 2010-05-26)
[Abstract] Okadaic acid (OA) is a phycotoxin produced by several types of dinoflagellates causing diarrheic shellfish poisoning (DSP) in humans. Symptoms induced by DSP toxins are mainly gastrointestinal, but the intoxication ...
The Organic Selenium Compound Selenomethionine Modulates Bleomycin-Induced DNA Damage and Repair in Human Leukocytes
(Springer, 2009-05-08)
[Abstract] The objective of this work was to evaluate the effects of selenomethionine (SeMet) on the induction, repair, and persistence of DNA damage in human leukocytes challenged with bleomycin (BLM). Comet assay was ...
Polymer-Supported Oxidovanadium(IV) Complexes and Their Catalytic Applications in One-Pot Multicomponent Reactions Producing Biologically Active 2,4,5-Trisubstituted-1H-imidazoles
(MDPI, 2023-03-19)
[Abstract] Two new monobasic tridentate O⁀N⁀N donor ligands, HL1 (I) and HL2 (II) have been obtained in two steps by reacting phenylhydrazine and salicylaldehyde or 3,5-di-tert-butylsalicylaldehyde and then reacting the ...
Mononuclear/Binuclear [VIVO]/[VVO2] Complexes Derived from 1,3-Diaminoguanidine and Their Catalytic Application for the Oxidation of Benzoin via Oxygen Atom Transfer
(ACS, 2023-01-10)
[Abstract] Ligands H4sal-dag (I) and H4Brsal-dag (II) derived from 1,3-diaminoguanidine and salicylaldehyde or 5-bromosalicylaldehyde react with one or 2 mol equivalent of vanadium precursor to give two different series ...
First Iron(II) Organometallic Compound Acting as ABCB1 Inhibitor
(Elsevier, 2023-05-13)
[Abstract] Five new iron (II) complexes bearing imidazole-based (Imi-R) ligands with the general formula [Fe(η5-C5H5)(CO)(PPh3)(Imi-R)][CF3SO3] were synthesized and fully characterized by several spectroscopic and analytical ...
Assessing the in Vitro Toxicity of Airborne (Nano)Particles to the Human Respiratory System: From Basic to Advanced Models [Review]
(Taylor & Francis, 2023-01-24)
[Abstract] Several studies have been conducted to address the potential adverse health risks attributed to exposure to nanoscale materials. While in vivo studies are fundamental for identifying the relationship between ...