• Brachial pulse pressure in acute heart failure. Results of the Heart Failure Registry 

      Bonapace, Stefano; Rossi, Andrea; Laroche, Cécile; Crespo-Leiro, María Generosa; Piepoli, Massimo F.; Coats, Andrew J. S.; Dahlström, Ulf; Malek, Filip; Macarie, Cezar; Temporelli, Pier Luigi; Maggioni, Aldo P.; Tavazzi, Luigi (Willey Online Library, 2019-12-09)
      [Abstract] Aims To investigate the still uncertain independent prognostic impact of pulse pressure (PP) in acute heart failure (HF), in particular across the left ventricular ejection fraction (EF) phenotypes, and the ...
    • Characteristics of women with type 2 diabetes mellitus and heart failure in Spain: the DIABET-IC study 

      Rodríguez-Padial, Luis; Pérez, Antonio; Anguita Sánchez, Manuel; Barrios, Vivencio; Gimeno Orna, José Antonio; Muñiz, Javier (Via Medica, 2023-02-27)
      [Abstract] Background: Heart failure (HF) is the second most common initial presentation of cardiovascular disease in people with type 2 diabetes mellitus (T2DM). T2DM carries an increased risk of HF in women. The aim of ...
    • Chronic anemia in heart transplant patients: prevalence, risk factors, and prognostic significance 

      Cursack, Guillermo C.; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Muñiz, Javier; Naya, Carmen; Grille Cancela, Zulaika; Rodríguez-Fernández, José Ángel; Marzoa Rivas, Raquel; Barge-Caballero, Eduardo; Ríos, Ramón; Estévez, Francisco; Cuenca, José J.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2007)
      [Abstract] Introduction and objectives. Data on chronic anemia following heart transplantation (HT) are scarce and contradictory. Our aims were to determine the prevalence of chronic anemia after HT, to identify predisposing ...
    • Clinical Profile and Causes of Death According to Ejection Fraction in Patients With Heart Failure Cared for in a Specialized Cardiology Unit 

      Barge-Caballero, Eduardo; Montero-Fole, B.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Pardo-Martínez, Patricia; Sagastagoitia-Fornie, Marta; Muñiz, Javier; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2021-05-14)
      [Abstract] Background and objective. Patients with heart failure are classified into three phenotypes based on left ventricular ejection fraction. This work aimed to compare the clinical profile, treatment, prognosis, ...
    • Comparison of predicted and observed mortality in patients with heart failure treated at a specialized unit 

      Barge-Caballero, Eduardo; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Marzoa-Rivas, Raquel; Naya-Leira, Carmen; Riveiro-Rodríguez, Cristina M.; Grille-Cancela, Zulaika; Blanco-Canosa, Paula; Muñiz, Javier; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-01-21)
      [Abstract] Introduction and objectives: To analyze survival in heart failure (HF) patients treated at a specialized unit. Methods: Prospective cohort-based study of HF patients treated at a specialized unit from 2011 ...
    • Differences in outcome of heart failure with preserved or depressed systolic function in patients older than 70 years who receive beta blockers 

      Anguita, Manuel; Castillo, Juan C.; Ruiz, Martín; Castillo, Francisco; Jiménez-Navarro, Manuel; Crespo-Leiro, María Generosa; Alonso-Pulpón, Luis; Teresa Galván, Eduardo de; Castro-Beiras, Alfonso; Roig, Eulàlia; Artigas, Remei; Zapata, Antonio; López-de-Ullibarri, Ignacio; Muñiz, Javier (Elsevier, 2011-10-14)
      [Abstract] Introduction and objectives. Most studies have shown that prognosis of heart failure with preserved systolic function is as poor as that of heart failure with depressed systolic function, although these results ...
    • Effect of a training program for primary care physicians on the optimization of beta-blocker treatment in elderly patients with heart failure 

      Anguita, Manuel; Jiménez-Navarro, Manuel; Crespo-Leiro, María Generosa; Alonso-Pulpón, Luis; Teresa Galván, Eduardo de; Castro-Beiras, Alfonso; Roig, Eulàlia; Artigas, Remei; Zapata, Antonio; López-de-Ullibarri, Ignacio; Muñiz, Javier (Elsevier, 2010)
      [Abstract] Introduction and objectives. Underuse of beta-blockers may contribute to elevated mortality in chronic heart failure. The aim of this study was to determine whether a specific interventional training program for ...
    • Emery–Dreifuss muscular dystrophy Type 1 is associated with a high risk of malignant ventricular arrhythmias and end-stage heart failure 

      Martínez-Veira, Cristina; Cannie, Douglas E.; Syrris, Petros; Protonotarios, Alexandros; Bakalakos, Athanasios; Pruny, Jean-François; Ditaranto, Rafaello; Larrañaga-Moreira, José María; Medo, Kristen; Bermúdez-Jiménez, Francisco J.; Ben Yaou, Rabah; Leturcq, France; Robles-Mezcua, Ainhoa; Marini-Betolo, Chiara; Cabrera, Eva; Reuter, Chloe; Limeres-Freire, Javier; Rodríguez-Palomares, José Fernando; Mestroni, Luisa; Taylor, Matthew R. G.; Parikh, Victoria N.; Ashley, Euan A.; Barriales-Villa, Roberto; Jiménez-Jáimez, Juan; García-Pavía, Pablo; Charron, Philippe; Biagini, Elena; García-Pinilla, José Manuel; Bourke, John; Savvatis, Konstantinos; Wahbi, Karim; Elliott, Perry M. (Oxford Academic, 2023-08-28)
      [Abstract] Emery–Dreifuss muscular dystrophy (EDMD) is caused by variants in EMD (EDMD1) and LMNA (EDMD2). Cardiac conduction defects and atrial arrhythmia are common to both, but LMNA variants also cause end-stage heart ...
    • Exon-skipping brain natriuretic peptide variant is overexpressed in failing myocardium and attenuates brain natriuretic peptide production in vitro 

      Torrado, Mario; Iglesias Reinoso, Raquel; Centeno, Alberto; López, Eduardo; Mikhailov, Alexander T. (SAPE / Society for Experimental Biology and Medicine, 2010)
      [Abstract] Brain natriuretic peptide/natriuretic peptide precursor B (NPPB) is one of the most studied genes in relation to heart failure (HF) conditions. However, it is still unclear as to whether alternative splicing ...
    • Gender Differences in Health-Related Quality of Life in Patients with Systolic Heart Failure: Results of the VIDA Multicenter Study 

      Garay, Alberto; Tapia, Javier; Anguita, Manuel; Formiga, Francesc; Almenar, Luis; Crespo-Leiro, María Generosa; Manzano, Luis; Muñiz, Javier; Chaves, José; Frutos, Trinidad de; Moliner, Pedro; Corbella, Xavier; Enjuanes, Cristina; Comín-Colet, Josep (MDPI AG, 2020-08-31)
      [Abstract] Previous studies have shown that heart failure is associated with worse health-related quality of life (HRQoL). The existence of differences according to gender remains controversial. We studied 1028 consecutive ...
    • Gene expression profiling for monitoring graft rejection in heart transplant recipients 

      Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Hermida-Prieto, Manuel; Castro-Beiras, Alfonso (Elsevier, 2009-08-26)
      [Abstract] Heart transplantation is a life-prolonging therapy for many patients with stage D heart failure and other forms of advanced heart disease. However, graft rejection and/or immunosuppression-related side effects ...
    • Heart Failure Association of the European Society of Cardiology heart failure nurse curriculum 

      Riley, Jilian P.; Astin, Felicity; Crespo-Leiro, María Generosa; Deaton, Christi M.; Kienhorst, Jens; Lambrinou, Ekaterini; McDonagh, Theresa A.; Rushton, Claire A.; Stromberg, Anna; Filippatos, Gerasimos; Anker, Stefan (Wiley, 2016-05-25)
      [Abstract] Recent advances in care and management of heart failure have improved outcome, largely as a result of the developing evidence basis for medications, implantable devices and the organization of heart failure ...
    • Intron retention generates ANKRD1 splice variants that are co-regulated with the main transcript in normal and failing myocardium 

      Torrado, Mario; Iglesias, Raquel; Nespereira, Beatriz; Centeno, Alberto; López, Eduardo; Mikhailov, Alexander T. (Elsevier, 2009-03-31)
      [Abstract] The cardiac ankyrin repeat domain 1 protein (ANKRD1, also known as CARP) has been extensively characterized with regard to its proposed functions as a cardio-enriched transcriptional co-factor and stress-inducible ...
    • Omecamtiv Mecarbil in Chronic Heart Failure With Reduced Ejection Fraction: GALACTIC‐HF Baseline Characteristics and Comparison With Contemporary Clinical Trials 

      Teerlink, John R.; Díaz, Rafael; Felker, G. Michael; McMurray, John J.V.; Metra, Marco; Solomon, Scott D.; Adams, Kirkwood F.; Anand, Inder; Arias‐Mendoza, Alexandra; Biering‐Sørensen, Tor; Böhm, Michael; Bonderman, Diana; Cleland, John G.F.; Corbalán, Ramón; Crespo-Leiro, María Generosa; Dahlström, Ulf; Echeverría Correa, Luis E.; Fang, James C.; Filippatos, Gerasimos; Fonseca, Cándida; Goncalvesova, Eva; Goudev, Assen R.; Howlett, Jonathan G.; Lanfear, David E.; Lund, Mayanna; Macdonald, Peter; Mareev, Vyacheslav; Momomura, Shin‐ichi; O'Meara, Eileen; Parkhomenko, Alexander; Ponikowski, Piotr; Ramires, Felix J.A.; Serpytis, Pranas; Sliwa, Karen; Spinar, Jindrich; Suter, Thomas M.; Tomcsanyi, Janos; Vandekerckhove, Hans; Vinereanu, Dragos; Voors, Adriaan A.; Yilmaz, Mehmet B.; Zannad, Faiez; Sharpsten, Lucie; Legg, Jason C.; Abbasi, Siddique A.; Varin, Claire; Malik, Fady I.; Kurtz, Christopher E. (Willey Online Library, 2020-09-20)
      [Abstract] Aims The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is being tested in the Global Approach ...
    • Prevalence of heart failure in the spanish general population aged over 45 years. the PRICE study 

      Anguita, Manuel; Crespo-Leiro, María Generosa; Teresa Galván, Eduardo de; Jiménez-Navarro, Manuel; Alonso-Pulpón, Luis; Muñiz, Javier (Elsevier, 2009-01-15)
      [Abstract] Introduction and objectives. Congestive heart failure is associated with substantial morbidity and mortality and both its incidence and prevalence are high. Nevertheless, comprehensive data on this condition in ...
    • Prognostic implications of atrial fibrillation in heart failure with reduced, mid-range, and preserved ejection fraction: a report from 14 964 patients in the European Society of Cardiology Heart Failure Long-Term Registry 

      Zafrir, Barak; Lund, Lars H.; Laroche, Cecile; Ruschitzka, Frank; Crespo-Leiro, María Generosa; Coats, Andrew J.S.; Anker, Stefan; Filippatos, Gerasimos; Seferovic, Petar M.; Maggioni, Aldo P.; Mora Martín, Manuel De; Polonski, Lech; Silva-Cardoso, José; Amir, Offer (Oxford, 2018-10-15)
      [Abstract] Aim. To investigate the characteristics long-term prognostic implications (up to ∼2.2 years) of atrial fibrillation (AF) compared to sinus rhythm (SR), between acute and chronic heart failure (HF) with reduced ...
    • Real World Comparison of Spironolactone and Eplerenone in Patients With Heart Failure 

      Pardo-Martínez, Patricia; Barge-Caballero, Eduardo; Bouzas-Mosquera, Alberto; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Sagastagoitia-Fornie, Marta; Prada-Delgado, Óscar; Muñiz, Javier; Almenar-Bonet, Luis; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2022-01-06)
      [Abstract] Aims. In the absence of previous direct comparative studies, we aimed to evaluate the effectiveness of spironolactone and eplerenone in patients with heart failure and reduced ejection fraction (HFrEF) in a ...
    • Serum Potassium Dynamics During Acute Heart Failure Hospitalization 

      Caravaca Pérez, Pedro; González-Juanatey, J.R.; Nuche, Jorge; Morán-Fernández, Laura; Lora Pablos, David; Álvarez-García, Jesús; Bascompte Claret, Ramón; Martínez-Sellés, Manuel; Vázquez García, Rafael; Martínez Dolz, Luis; Cobo-Marcos, Marta; Pascual Figal, Domingo A.; Crespo-Leiro, María Generosa; Núñez Villota, Julio; Cinca Cuscullola, Juan; Delgado-Jiménez, Juan F. (Springer, 2020-10-17)
      [Abstract] Background. Available information about prognostic implications of potassium levels alteration in the setting of acute heart failure (AHF) is scarce. Objectives. We aim to describe the prevalence of ...
    • Severe Heart Failure in the Setting of Inflammatory Cardiomyopathy With Likely Pathogenic Titin Variant 

      Ochoa Folmer, Juan Pablo; Mueller, Melina; Zwinger, Lilli; Klaassen, Sabine; Poller, Wolfgang; Montserrat Iglesias, Lorenzo; Klingel, Karine; Landmesser, Ulf; Heidecker, Bettina (Elsevier, 2022-04)
      No abstract available
    • Usefulness of the INTERMACS scale for predicting outcomes after urgent heart transplantation 

      Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Campo-Pérez, Rosa; Rodríguez-Fernández, José Ángel; Pérez-Pérez, Alberto; García-Bueno, Lourdes; Blanco-Canosa, Paula; Grille Cancela, Zulaika; Solla-Buceta, Miguel; Juffé-Stein, Alberto; Herrera-Noreña, José M.; Cuenca, José J.; Muñiz, Javier; Castro-Beiras, Alfonso; Crespo-Leiro, María Generosa (Elsevier, 2011)
      [Abstract] Introduction and objectives. Our aim was to assess the prognostic value of the INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) scale in patients undergoing urgent heart transplantation ...