Mostrar o rexistro simple do ítem
Ontologies in medicinal chemistry: current status and future challenges
dc.contributor.author | Gómez-Pérez, Asunción | |
dc.contributor.author | Martínez-Romero, Marcos | |
dc.contributor.author | Rodríguez-González, Alejandro | |
dc.contributor.author | Vázquez, Guillermo | |
dc.contributor.author | Vázquez-Naya, José | |
dc.date.accessioned | 2017-06-12T10:36:09Z | |
dc.date.available | 2017-06-12T10:36:09Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Gómez-Pérez A, Martínez-Romero M, Rodríguez-González A, Vázquez G, Vázquez-Naya JM. Ontologies in medicinal chemistry: current status and future challenges. Curr Top Med Chem. 2013;13(5):576-590 | es_ES |
dc.identifier.issn | 1568-0266 | |
dc.identifier.issn | 1873-4294 | |
dc.identifier.uri | http://hdl.handle.net/2183/19165 | |
dc.description.abstract | [Abstract] Recent years have seen a dramatic increase in the amount and availability of data in the diverse areas of medicinal chemistry, making it possible to achieve significant advances in fields such as the design, synthesis and biological evaluation of compounds. However, with this data explosion, the storage, management and analysis of available data to extract relevant information has become even a more complex task that offers challenging research issues to Artificial Intelligence (AI) scientists. Ontologies have emerged in AI as a key tool to formally represent and semantically organize aspects of the real world. Beyond glossaries or thesauri, ontologies facilitate communication between experts and allow the application of computational techniques to extract useful information from available data. In medicinal chemistry, multiple ontologies have been developed during the last years which contain knowledge about chemical compounds and processes of synthesis of pharmaceutical products. This article reviews the principal standards and ontologies in medicinal chemistry, analyzes their main applications and suggests future directions. | es_ES |
dc.description.sponsorship | Instituto de Salud Carlos III; FIS-PI10/02180 | es_ES |
dc.description.sponsorship | Programa Iberoamericano de Ciencia y Tecnología para el Desarrollo; 209RT0366 | es_ES |
dc.description.sponsorship | Galicia. Consellería de Cultura, Educación e Ordenación Universitaria; CN2012/217 | es_ES |
dc.description.sponsorship | Galicia. Consellería de Cultura, Educación e Ordenación Universitaria; CN2011/034 | es_ES |
dc.description.sponsorship | Galicia. Consellería de Cultura, Educación e Ordenación Universitaria; CN2012/211 | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Bentham Science | es_ES |
dc.relation.uri | http://dx.doi.org/10.2174/1568026611313050003 | es_ES |
dc.rights | The published manuscript is avaliable at EurekaSelect | es_ES |
dc.subject | Drug design | es_ES |
dc.subject | Drug discovery | es_ES |
dc.subject | Medicinal chemistry | es_ES |
dc.subject | Ontologies | es_ES |
dc.subject | Semantic web | es_ES |
dc.title | Ontologies in medicinal chemistry: current status and future challenges | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.access | info:eu-repo/semantics/openAccess | es_ES |
UDC.journalTitle | Current Topics in Medicinal Chemistry | es_ES |
UDC.volume | 13 | es_ES |
UDC.issue | 5 | es_ES |
UDC.startPage | 576 | es_ES |
UDC.endPage | 590 | es_ES |
Ficheiros no ítem
Este ítem aparece na(s) seguinte(s) colección(s)
-
GI-RNASA - Artigos [195]
-
INIBIC-RNASA-IMEDIR - Artigos [46]