• Genomic Analysis of Molecular Bacterial Mechanisms of Resistance to Phage Infection 

      Ambroa, Antón; Blasco, Lucía; López, María; Pacios Santamaría, Olga; Bleriot Rial, Ines; Fernández-García, Laura; González de Aledo, Manuel; Ortiz-Cartagena, Concha; Millard, Andrew; Tomás, María (Frontiers, 2022-02-17)
      [Abstract] To optimize phage therapy, we need to understand how bacteria evolve against phage attacks. One of the main problems of phage therapy is the appearance of bacterial resistance variants. The use of genomics to ...
    • Involvement of HisF in the persistence of Acinetobacter baumannii during a pneumonia infection 

      Martínez-Guitián, Marta; Vázquez-Ucha, Juan Carlos; Álvarez-Fraga, Laura; Conde-Pérez, Kelly; Lasarte-Monterrubio, Cristina; Vallejo, J. A.; Bou, Germán; Poza, Margarita; Beceiro, Alejandro (Frontiers, 2019)
      [Abstract] Acinetobacter baumannii is currently considered one of themost problematic nosocomial microorganisms. In the present work the hisF gene from the ATCC 17978 strain and the AbH12O-A2 clinical isolate of A. baumannii ...
    • Quorum Sensing as a Target for Controlling Surface Associated Motility and Biofilm Formation in Acinetobacter Baumannii ATCC® 17978TM 

      Mayer, Celia; Muras, Andrea; Parga, Ana; Romero, Manuel; Rumbo-Feal, Soraya; Poza, Margarita; Ramos Vivas, Jose; Otero, Ana (Frontiers, 2020-09-30)
      [Abstract] The important nosocomial pathogen Acinetobacter baumannii presents a quorum sensing (QS) system (abaI/abaR) mediated by acyl-homoserine-lactones (AHLs) and several quorum quenching (QQ) enzymes. However, the ...