Listar II - Artigos por autor "Ambroa, Antón"

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    • Genomic Analysis of Molecular Bacterial Mechanisms of Resistance to Phage Infection 

      Ambroa, Antón; Blasco, Lucía; López, María; Pacios Santamaría, Olga; Bleriot Rial, Ines; Fernández-García, Laura; González de Aledo, Manuel; Ortiz-Cartagena, Concha; Millard, Andrew; Tomás, María (Frontiers, 2022-02-17)
      [Abstract] To optimize phage therapy, we need to understand how bacteria evolve against phage attacks. One of the main problems of phage therapy is the appearance of bacterial resistance variants. The use of genomics to ...

    • Phenotypic and Genomic Comparison of Klebsiella pneumoniae Lytic Phages: vB_KpnM-VAC66 and vB_KpnM-VAC13 

      Pacios Santamaría, Olga; Fernández-García, Laura; Bleriot Rial, Ines; Blasco, Lucía; Ambroa, Antón; López, María; Ortiz-Cartagena, Concha; Fernández Cuenca, Felipe; Oteo, Jesús; Pascual, Álvaro; Martínez Martínez, Luis; Domingo-Calap, Pilar; Tomás, María (MDPI, 2021-12-21)
      [Abstract] Klebsiella pneumoniae is a human pathogen that worsens the prognosis of many immunocompromised patients. Here, we annotated and compared the genomes of two lytic phages that infect clinical strains of K. pneumoniae ...

    • The Role of PemIK (PemK/PemI) Type II TA System from Klebsiella pneumoniae Clinical Strains in Lytic Phage Infection 

      Bleriot Rial, Ines; Blasco, Lucía; Pacios Santamaría, Olga; Fernández-García, Laura; Ambroa, Antón; López, María; Ortiz-Cartagena, Concha; Fernández Cuenca, Felipe; Oteo, Jesús; Pascual, Álvaro; Martínez Martínez, Luis; Domingo-Calap, Pilar; Wood, Thomas K.; Tomás, María (Springer Nature, 2022-03-16)
      [Abstract] Since their discovery, toxin-antitoxin (TA) systems have captivated the attention of many scientists. Recent studies have demonstrated that TA systems play a key role in phage inhibition. The aim of the present ...