• Kpi, a Chaperone-Usher Pili System Associated with the Worldwide-Disseminated High-Risk Clone Klebsiella Pneumoniae ST-15 

      Gato, Eva; Vázquez-Ucha, Juan Carlos; Rumbo-Feal, Soraya; Álvarez-Fraga, Laura; Vallejo, J. A.; Martínez-Guitián, Marta; Beceiro, Alejandro; Ramos Vivas, Jose; Sola-Campoy, Pedro Juan; Pérez-Vázquez, María; Oteo, Jesús; Rodiño-Janeiro, Bruno Kotska; Romero, Antonio; Poza, Margarita; Bou, Germán; Pérez, Astrid (National Academy of Sciences, 2020-07-08)
      [Abstract] Control of infections caused by carbapenem-resistant Klebsiella pneumoniae continues to be challenging. The success of this pathogen is favored by its ability to acquire antimicrobial resistance and to spread ...
    • Phenotypic and Genomic Comparison of Klebsiella pneumoniae Lytic Phages: vB_KpnM-VAC66 and vB_KpnM-VAC13 

      Pacios Santamaría, Olga; Fernández-García, Laura; Bleriot Rial, Ines; Blasco, Lucía; Ambroa, Antón; López, María; Ortiz-Cartagena, Concha; Fernández Cuenca, Felipe; Oteo, Jesús; Pascual, Álvaro; Martínez Martínez, Luis; Domingo-Calap, Pilar; Tomás, María (MDPI, 2021-12-21)
      [Abstract] Klebsiella pneumoniae is a human pathogen that worsens the prognosis of many immunocompromised patients. Here, we annotated and compared the genomes of two lytic phages that infect clinical strains of K. pneumoniae ...
    • The Role of PemIK (PemK/PemI) Type II TA System from Klebsiella pneumoniae Clinical Strains in Lytic Phage Infection 

      Bleriot Rial, Ines; Blasco, Lucía; Pacios Santamaría, Olga; Fernández-García, Laura; Ambroa, Antón; López, María; Ortiz-Cartagena, Concha; Fernández Cuenca, Felipe; Oteo, Jesús; Pascual, Álvaro; Martínez Martínez, Luis; Domingo-Calap, Pilar; Wood, Thomas K.; Tomás, María (Springer Nature, 2022-03-16)
      [Abstract] Since their discovery, toxin-antitoxin (TA) systems have captivated the attention of many scientists. Recent studies have demonstrated that TA systems play a key role in phage inhibition. The aim of the present ...