ListarGrupos de investigación por tema "GWAS"

Mostrando ítems 1-5 de 5

    • Fast search of third-order epistatic interactions on CPU and GPU clusters 

      Ponte-Fernández, Christian; González-Domínguez, Jorge; Martín, María J. (Sage Publications Ltd., 2019-05-27)
      [Abstract] Genome-Wide Association Studies (GWASs), analyses that try to find a link between a given phenotype (such as a disease) and genetic markers, have been growing in popularity in the recent years. Relations between ...

    • Fiuncho: a program for any-order epistasis detection in CPU clusters 

      Ponte-Fernández, Christian; González-Domínguez, Jorge; Martín, María J. (Springer, 2022)
      [Abstract]: Epistasis can be defined as the statistical interaction of genes during the expression of a phenotype. It is believed that it plays a fundamental role in gene expression, as individual genetic variants have ...

    • GPU-accelerated exhaustive search for third-order epistatic interactions in case–control studies 

      González-Domínguez, Jorge; Schmidt, Bertil (Elsevier Ltd, 2015)
      [Abstract] Interest in discovering combinations of genetic markers from case–control studies, such as Genome Wide Association Studies (GWAS), that are strongly associated to diseases has increased in recent years. Detecting ...

    • High-speed exhaustive 3-locus interaction epistasis analysis on FPGAs 

      Kässens, Jan Christian; Wienbrandt, Lars; González-Domínguez, Jorge; Schmidt, Bertil; Schimmler, Manfred (Elsevier B.V., 2015-07)
      [Abstract]: Epistasis, the interaction between genes, has become a major topic in molecular and quantitative genetics. It is believed that these interactions play a significant role in genetic variations causing complex ...

    • Hybrid CPU/GPU Acceleration of Detection of 2-SNP Epistatic Interactions in GWAS 

      González-Domínguez, Jorge; Schmidt, Bertil; Kässens, Jan Christian; Wienbrandt, Lars (Springer, 2014-08)
      [Abstract] High-throughput genotyping technologies allow the collection of up to a few million genetic markers (such as SNPs) of an individual within a few minutes of time. Detecting epistasis, such as 2-SNP interactions, ...