Mostrando ítems 146-150 de 193

    • Evolutionary Computation and QSAR Research 

      Aguiar-Pulido, Vanessa; Gestal, M.; Cruz-Monteagudo, Maykel; Rabuñal, Juan R.; Dorado, Julián; Munteanu, Cristian-Robert (Bentham Science, 2013)
      [Abstract] The successful high throughput screening of molecule libraries for a specific biological property is one of the main improvements in drug discovery. The virtual molecular filtering and screening relies greatly ...
    • Improving Enzyme Regulatory Protein Classification by Means of SVM-RFE Feature Selection 

      Fernández-Lozano, Carlos; Fernández-Blanco, Enrique; Dave, Kirtan; Pedreira Souto, Nieves; Gestal, M.; Dorado, Julián; Munteanu, Cristian-Robert (Royal Society of Chemistry, 2014-01-14)
      [Abstract] Enzyme regulation proteins are very important due to their involvement in many biological processes that sustain life. The complexity of these proteins, the impossibility of identifying direct quantification ...
    • A semantic interoperability approach to support integration of gene expression and clinical data in breast cancer 

      Alonso-Calvo, Raúl; Paraíso-Medina, Sergio; Pérez-Rey, David; Alonso-Oset, Enrique; Stiphout, Ruud van; Taylor, Marian; Buffa, Francesca; Fernández-Lozano, Carlos; Pazos, A.; Maojo, Víctor (Elsevier, 2017-06-05)
      [Abstract] Introduction. The introduction of omics data and advances in technologies involved in clinical treatment has led to a broad range of approaches to represent clinical information. Within this context, patient ...
    • Ontologies in medicinal chemistry: current status and future challenges 

      Gómez-Pérez, Asunción; Martínez-Romero, Marcos; Rodríguez-González, Alejandro; Vázquez, Guillermo; Vázquez-Naya, José (Bentham Science, 2013)
      [Abstract] Recent years have seen a dramatic increase in the amount and availability of data in the diverse areas of medicinal chemistry, making it possible to achieve significant advances in fields such as the design, ...
    • Parallel computing for brain simulation 

      Pastur-Romay, L.A.; Porto-Pazos, Ana B.; Cedrón, Francisco; Pazos, A. (Bentham Science, 2017-05-01)
      [Abstract] Background: The human brain is the most complex system in the known universe, it is therefore one of the greatest mysteries. It provides human beings with extraordinary abilities. However, until now it has not ...