Browsing Diagnóstico molecular e condutual aplicado á saúde (DICOMOSA) by Author "Delgado-Zayas, Enrique"
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Analysis of Four Polymorphisms Located at the Promoter of the Estrogen Receptor Alpha ESR1 Gene in a Population With Gender Incongruence
Fernández, Rosa; Delgado-Zayas, Enrique; Ramírez, Karla; Cortés-Cortés, Joselyn; Gómez-Gil, Esther; Esteva de Antonio, Isabel; Almaraz, María Cruz; Guillamón, Antonio; Pásaro, Eduardo (2020)[Abstract] Introduction: Gender incongruence defines a state in which individuals feel discrepancy between the sex assigned at birth and their gender. Some of these people make a social transition from male to female ... -
Epigenetics Is Implicated in the Basis of Gender Incongruence: An Epigenome-Wide Association Analysis
Ramirez, Karla; Fernández, Rosa; Collet, Sarah; Meltem, Kiyat; Delgado-Zayas, Enrique; Gómez-Gil, Esther; Van Den Eynde, Tibbert; T’Sjoen, Guy; Guillamon, Antonio; Mueller, Sven C.; Pásaro, Eduardo (2021)[Abstract] Introduction: The main objective was to carry out a global DNA methylation analysis in a population with gender incongruence before gender-affirming hormone treatment (GAHT), in comparison to a cisgender ... -
Implications of the Estrogen Receptor Coactivators SRC1 and SRC2 in the Biological Basis of Gender Incongruence
Del Valle Ramírez, Karla; Fernández, Rosa; Delgado-Zayas, Enrique; Gómez-Gil, Esther; Esteva de Antonio, Isabel; Guillamon, Antonio; Pásaro, Eduardo (2021)[Abstract] Introduction Brain sexual differentiation results from the effects of sex steroids on the developing brain. The presumptive route for brain masculinization is the direct induction of gene expression via activation ...