• Searching for Hif1-α interacting proteins in renal cell carcinoma 

      Medina Villaamil, Vanessa; Aparicio Gallego, Guadalupe; Santamarina, Isabel; Valladares-Ayerbes, Manuel; Antón-Aparicio, Luis M. (Springer para Federation of Spanish Oncology Sociesties (FESEO), 2012-08-28)
      [Abstract] Introduction. Kidney tumours are frequently characterised by hypoxic conditions due to a local imbalance between oxygen (O2) supply and consumption. Hif1-α regulates angiogenesis, tumour growth, tumour progression, ...
    • Tyrosine kinase inhibitors reprogramming immunity in renal cell carcinoma: rethinking cancer immunotherapy 

      Antón-Aparicio, Luis M.; Peláez Fernández, Ignacio; Cassinello Espinosa, J. (Springer, 2017-04-13)
      [Abstract] The immune system regulates angiogenesis in cancer by way of both pro- and antiangiogenic activities. A bidirectional link between angiogenesis and the immune system has been clearly demonstrated. Most antiangiogenic ...