• Clinical manifestations and diagnosis of acromegaly 

      Lugo, Gloria; Pena, Lara; Cordido, Fernando (Hindawi, 2012)
      [Abstract] Acromegaly and gigantism are due to excess GH production, usually as a result of a pituitary adenoma. The incidence of acromegaly is 5 cases per million per year and the prevalence is 60 cases per million. ...
    • Ghrelin in obesity, physiological and pharmacological considerations 

      Álvarez-Castro, Paula; Pena, Lara; Cordido, Fernando (Bentham, 2013-04)
      [Abstract] The aim of this review is to summarize the physiological and pharmacological aspects of ghrelin. Obesity can be defined as an excess of body fat and is associated with significant disturbances in metabolic and ...
    • Place of preoperative treatment of acromegaly with somatostatin analog on surgical outcome: a systematic review and meta-analysis 

      Pita-Gutiérrez, Francisco; Pértega-Díaz, Sonia; Pita-Fernández, Salvador; Pena, Lara; Lugo, Gloria; Sangiao-Alvarellos, Susana; Cordido, Fernando (PLoS ONE, 2013-04-25)
      [Abstract] Context. Transsphenoidal neurosurgery is the accepted first-line treatment of acromegaly in the majority of patients. Previous studies addressing preoperative somatostatin analog (SSA) treatment and subsequent ...